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214597 Sidt2

214597

Sidt2

SID1 transmembrane family, member 2

protein-coding

Mus musculus

基因描述

Type Description
Definition SID1 transmembrane family, member 2

研究结论

Date Results Publications
2019-07-27 11:12:00 The Sidt2 plays an important role in mouse hepatic lipid homeostasis by regulating autophagy at the terminal stage. 29363559
2018-05-05 10:05:00 This study provides new insight into lysosomal targeting of proteins and intracellular RNA degradation, and further confirms the critical function of SIDT2 in RNautophagy. 28724756
2017-12-09 12:47:00 SIDT2 (SID1 transmembrane family, member 2), an ortholog of the Caenorhabditis elegans putative RNA transporter SID-1 (systemic RNA interference defective-1), mediates RNA translocation during RNautophagy 27846365
2017-10-28 12:39:00 We conclude that Sidt2 is involved in NAADP-mediated release of calcium from insulin secretory granules and thus regulates insulin secretion. 26744456
2017-10-21 12:24:00 SIDT2, is required to transport internalized extracellular dsRNA from endocytic compartments into the cytoplasm for immune activation. Sidt2-deficient mice exposed to extracellular dsRNA, encephalomyocarditis virus (EMCV), and herpes simplex virus 1 (HSV-1) show impaired production of antiviral cytokines and-in the case of EMCV and HSV-1-reduced survival. 28916264

名称对应

Type IDs
Synonymous B930096O19, BC023957, CGI-40
Gene
UniProtKB-ID: SIDT2_MOUSE, Q3U1L8_MOUSE
UniprotKB: Q8CIF6, Q3U1L8
UniParc: UPI000018D51B, UPI000002721B
EMBL: BC006873, BC051101, BC023957, AK155875
Ensembl: ENSMUSG00000034908
KO: mmu:214597
Nucleutide sequences
EMBL-CDS: AAH06873.1, AAH51101.1, AAH23957.1, BAE33477.1
Ensembl_TRS: ENSMUST00000114573, ENSMUST00000038488
Protein sequencees
Ensembl_PRO: ENSMUSP00000044290, ENSMUSP00000110220
RefSeq: XP_006510207.1, XP_006510205.1, XP_006510204.1, NP_001276597.1, XP_006510208.1, XP_006510206.1, NP_001346582.1, NP_758461.1
Others
UniRef100: UniRef100_Q8CIF6
UniRef90: UniRef90_Q8CIF6
UniRef50: UniRef50_Q8CIF6
UniGene: Mm.379345
CCDS: CCDS23138.1, CCDS72225.1

全选

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