| Type | Description |
|---|---|
| Definition | dual oxidase 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-02-23 13:33:00 | All these results reveal a critical role of Duox2 in the infection-induced H2O2 production and the H2O2-mediated immune response to infection in the respiratory tract. | 29556357 |
| 2018-12-22 11:54:00 | The findings illustrate for the first time that the extreme C-terminus of Duox2 is required for the functional activity of the enzyme . | 29373314 |
| 2018-10-27 11:25:00 | Duox2 is necessary for the regulation of IFN secretion in in vivo lung, and pulmonary administration of Duox2 DNA using cationic polymer triggers the induction of type I and III IFNs resulting in more complete suppression of influenza A virus infection. | 28936773 |
| 2017-12-02 12:11:00 | Both Nox1 and Duox2 induce exfoliation of crypt epithelium, but only Nox1 induces apoptosis. NOX1 and DUOX2 may be potential therapeutic targets for treating ileocolitis in human patients suffering inflammatory bowel disease (IBD). | 27930931 |
| 2017-12-02 11:57:00 | dual oxidase-2 and IL-6 play important roles in GPR43-mediated skin inflammation. | 28212864 |
| Type | IDs |
|---|---|
| Synonymous | A430065P05Rik, LNOX2, NOXEF2, P138-TOX, THOX2 |
| Gene |
UniProtKB-ID:
A0A494BAW1_MOUSE
UniprotKB:
A0A494BAW1
UniParc:
UPI0001F78A23
EMBL:
AL844566
Ensembl:
ENSMUSG00000068452
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000237546
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000158204
RefSeq:
NP_001349684.1,
XP_006499173.1
|
| Others |
UniRef100:
UniRef100_A0A494BAW1
UniRef90:
UniRef90_Q9ES45
UniRef50:
UniRef50_Q9NRD8
UniGene:
Mm.358846
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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