| Type | Description |
|---|---|
| Definition | SPG11, spatacsin vesicle trafficking associated |
| Date | Results | Publications |
|---|---|---|
| 2018-02-24 11:44:00 | Spg11 knockout mice developed early-onset motor impairment and cognitive deficits. These behavioral deficits were associated with progressive brain atrophy with the loss of neurons in the brain, as well as with accumulation of dystrophic axons in the corticospinal tract. Spinal motor neurons also degenerated and this was accompanied by fragmentation of neuromuscular junctions and muscle atrophy. | 28237315 |
| 2015-04-25 11:45:00 | Study provides evidence that SPG11 is implicated in axonal maintenance and cargo trafficking. | 24794856 |
| Type | IDs |
|---|---|
| Synonymous | 6030465E24Rik, A330015I11, C530005A01Rik |
| Gene |
UniProtKB-ID:
SPTCS_MOUSE
UniprotKB:
Q3UHA3
UniParc:
UPI0000D778FF,
UPI0000026FA6
EMBL:
AK049617,
AK049236,
AL845457,
AK039286,
AK147500,
AK129453,
BC019404,
AK083468
Ensembl:
ENSMUSG00000033396
KO:
mmu:214585
|
| Nucleutide sequences |
EMBL-CDS:
BAC33628.1,
BAC38926.1,
BAC33842.1,
AAH19404.1,
BAC30307.1,
BAE27954.1,
BAC98263.1
Ensembl_TRS:
ENSMUST00000036450
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000037543
RefSeq:
NP_663506.2,
XP_011237725.1,
XP_011237724.1
|
| Others |
UniRef100:
UniRef100_Q3UHA3
UniRef90:
UniRef90_Q3UHA3
UniRef50:
UniRef50_Q96JI7
UniGene:
Mm.222303
CCDS:
CCDS50687.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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