Tdrd5 - tudor domain containing 5-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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214575 Tdrd5

基因描述

Type	Description
Definition	tudor domain containing 5

研究结论

Date	Results	Publications
2019-09-28 11:47:00	By conditional inactivation of Tdrd5 in postnatal male germ cells (Tdrd5cKO), we show that spermatogenesis is arrested at the round spermatid stage, and the testes of Tdrd5cKO mice are about half the weight of wildtype controls.	29733347
2018-12-22 10:21:00	Conditional inactivation of TDRD5 in mouse postnatal germ cells reveals that TDRD5 selectively regulates the production of pachytene piRNAs from abundant piRNA-producing precursors, with little effect on low-abundant piRNAs.	29317670
2011-07-09 10:49:00	TDRD5 is a novel component of the intermitochondrial cements (IMCs) and the chromatoid bodies (CBs), which are cytoplasmic ribonucleoprotein granules involved in RNA processing for spermatogenesis.	21383078
2010-01-21 00:00:00	Tdrd5 expression is restricted to the male germline throughout development to adulthood	15465492

名称对应

Type	IDs
Synonymous	Gm103
Gene	UniProtKB-ID: TDRD5_MOUSE, J3QPB7_MOUSE UniprotKB: Q5VCS6, J3QPB7 UniParc: UPI00015C702F, UPI00015DF6A9, UPI0001611481 EMBL: BC099972, AK133026, AY522557, AC161414, AK132674, FQ976560 Ensembl: ENSMUSG00000060985 KO: mmu:214575
Nucleutide sequences	EMBL-CDS: AAH99972.1, AAU04873.1 Ensembl_TRS: ENSMUST00000121146, ENSMUST00000167528
Protein sequencees	Ensembl_PRO: ENSMUSP00000137298, ENSMUSP00000137182 RefSeq: XP_006496791.1, XP_036019385.1, NP_001128213.1, XP_006496789.1, XP_006496795.1, XP_006496797.1, XP_006496796.1, XP_006496790.1, XP_006496794.1, XP_006496792.1, XP_030108724.1, XP_011237082.1, NP_001264659.1, XP_006496793.1
Others	UniRef100: UniRef100_J3QPB7, UniRef100_Q5VCS6 UniRef90: UniRef90_Q5VCS6-2, UniRef90_Q5VCS6 UniRef50: UniRef50_Q5VCS6 UniGene: Mm.252800 CCDS: CCDS56647.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
31932482	ZFP628 Is a TAF4b-Interacting Transcription Factor Required for Mouse Spermiogenesis. Mol. Cell. Biol. Eric A Gustafson , Kimberly A Seymour , Kirsten Sigrist , Dirk G D E Rooij , Richard N Freiman	2020-03-16	-
29733347	Disruption of Tdrd5 decouples the stepwise processing of long precursor transcripts during pachytene PIWI-interacting RNA biogenesis. Biol. Reprod. Yu H Sun , Feng Jiang , Xin Zhiguo Li	2018-10-01	-
29317670	TDRD5 binds piRNA precursors and selectively enhances pachytene piRNA processing in mice. Nat Commun Deqiang Ding , Jiali Liu , Uros Midic , Yingjie Wu , Kunzhe Dong , Ashley Melnick , Keith E Latham , Chen Chen	2018-01-09	-
21383078	TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice. J Cell Biol Yukihiro Yabuta , Hiroshi Ohta , Takaya Abe , Kazuki Kurimoto , Shinichiro Chuma , Mitinori Saitou	2011-03-07	-
21931791	Defining the molecular character of the developing and adult kidney podocyte. PLoS ONE Eric W Brunskill , Kylie Georgas , Bree Rumballe , Melissa H Little , S Steven Potter	2011-01-01	Synpo, Gpsm3, Mgat5, Srgap1, Cdkn1c, Gadd45a, Dpp4, Efnb1, Enpep, Eya4, Foxc2, Rhpn1, Foxd1, Itga3, Jun, Mafb, Nphs2, Gadd45b, Nes, Npr3, Plat, Ptpro, Mtss1, Plekhh2, Tdrd5, Wt1, Clic5, Cdc14a, Arhgap24, Gadd45g, Angptl2, Podxl, Magi2, Iqgap2, Nphs1, Sncaip, Optn, Pard3b, Sgip1
21991325	RSPO1/Î²-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary. PLoS ONE Anne-Amandine Chassot , Elodie P Gregoire , Rowena Lavery , Makoto M Taketo , Dirk G de Rooij , Ian R Adams , Marie-Christine Chaboissier	2011-01-01	-
21386911	Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. PLoS ONE Rathi D Thiagarajan , Kylie M Georgas , Bree A Rumballe , Emmanuelle Lesieur , Han Sheng Chiu , Darrin Taylor , Dave T P Tang , Sean M Grimmond , Melissa H Little	2011-01-01	1110002E22Rik, Emilin1, Itga9, Smek2, Slc17a3, Gpsm3, Me2, Kazald1, Aldh1l1, Ccdc86, Mybpc1, Npy, Slc18a1, Ugt2b37, Foxp2, Ace, Ehbp1l1, Slc13a3, Adcy8, Ambp, Acsm1, Apoa4, Nr2f2, Synpo2, Bmp2, C2, Cacnb4, Capg, Casp4, Entpd5, Cdh11, Cideb, Col3a1, Col9a1, Csrp1, Cyp1b1, Cyp4a10, Dkk1, Dpep1, S1pr3, Eya1, F10, Fbp2, Fbp1, Slc6a13, Gpd1, Gnb4, Gng2, Gpm6b, Gria4, Gk, Hdc, Hhex, Hoxa10, Hpgd, Hpn, Elavl1, Elavl4, Igf1, Jag1, Napsa, Khsrp, Aff3, Lgals1, Lhx1, Stard4, Rbm39, Ly86, Edaradd, Kitl, Mlf1, Nxph1, Slc22a6, Pdgfra, Pgf, Prlr, Pipox, Ptn, Ttc36, Rem1, Rgs5, Nr1h4, Scnn1b, Sord, Sema3b, Slc23a1, Slc3a1, Serpini1, Stc2, Clic6, Tcn2, Tdrd5, Rassf2, Mfsd4b1, BC089597, Myo15b, Serpina10, Tgfb1i1, Tgfbi
19000842	Atlas of gene expression in the developing kidney at microanatomic resolution. Dev. Cell Eric W Brunskill , Bruce J Aronow , Kylie Georgas , Bree Rumballe , M Todd Valerius , Jeremy Aronow , Vivek Kaimal , Anil G Jegga , Jing Yu , Sean Grimmond , Andrew P McMahon , Larry T Patterson , Melissa H Little , S Steven Potter	2008-11-01	-
18287559	GUDMAP: the genitourinary developmental molecular anatomy project. J Am Soc Nephrol Andrew P McMahon , Bruce J Aronow , Duncan R Davidson , Jamie A Davies , Kevin W Gaido , Sean Grimmond , James L Lessard , Melissa H Little , S Steven Potter , Elizabeth L Wilder , Pumin Zhang , GUDMAP project	2008-04-01	-
17015433	Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo. Genes Dev. Alexei V Evsikov , Joel H Graber , J Michael Brockman , Ales Hampl , Andrea E Holbrook , Priyam Singh , John J Eppig , Davor Solter , Barbara B Knowles	2006-10-01	Oog3, Gm10637, Cphx2, Gm10436, Gm15501, Gm3139, Gm3143, Gm3259, Gm3286, Gm4566, Gm14635, Gm11238, Gm12130, Gm38425, Oas1d, Nfxl1, A730082K24Rik, Mtus1, Dcun1d2, Lrrc49, Ndufb11, Golm1, Chmp7, Cmc4, AU021063, Cops8, Rnf20, 2610305D13Rik, Serpinc1, Bmp15, Birc6, Aspm, Cnih1, Daxx, Ebp, Mark2, Epc1, Fgfr2, Fkbp2, Fkbp8, Gart, Gclm, Gpr19, Trip12, Hnrnpc, Eif2ak1, Ica1, Itpr1, Lama5, Lamc2, Glcci1, Mfap2, Mtf1, Mthfd2, Usp34, Myo5b, Nf2, Nfyc, Nudc, Odf2, Omt2a, Slc25a15, Igbp1, Per3, Pex7, Abcb1b, Plaa, Plat, Ppp5c, Proc, Ptprr, Oog1, Gm13103, Klf11, Rdx, Rnaseh1, Trim30a, Siah1b, Bptf, Spin1, Esrp1, Aurkc, Fanci, Surf4, Suv39h1, Pdlim2, Tcl1, Tdrd5, Mcu, Os9, Clint1, Heatr6, Gm11545, Tex264, Cirh1a, Eif4e1b, Top1, Ttk, Ubc

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