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21454 Tcp1

21454

Tcp1

t-complex protein 1

protein-coding

Mus musculus

基因描述

Type Description
Definition t-complex protein 1

研究结论

Date Results Publications
2018-09-22 12:04:00 chaperonin-containing TCP-1 complex required for lysosomal functioning and autophagosome degradation 27929117
2018-09-01 12:04:00 The authors identify and confirm interaction of M72 with the eukaryotic chaperonin tailless complex protein -1 (TCP-1) ring complex (TRiC) or chaperonin containing tailless complex polypeptide 1 (CCT). Accumulating biochemical evidence indicates M72 forms homo-oligomers and is a substrate of TRiC/CCT 30029015
2018-01-27 11:42:00 treating BACHD cortical neurons with ApiCCT1 prevented BACHD striatal neuronal atrophy by enhancing release of BDNF that subsequently acts through tyrosine receptor kinase B (TrkB) receptor on striatal neurons. Our findings are evidence that TRiC reagent-mediated reductions in mHTT enhanced BDNF delivery to restore the trophic status of BACHD striatal neurons. 27601642
2017-07-01 11:33:00 this study shows that CCTalpha is required for antigen-specific, germinal center-derived memory B cells 27502364
2016-10-01 12:28:00 Data show that T-complex protein 1 (TCP-1) may be a crucial downstream molecule of purinergic receptor P2X 7 (P2X7R) and plays a role in lymphoid neoplasm metastasis. 26556873

名称对应

Type IDs
Synonymous AI528772, CCT, Cct1, Ccta, TRic, Tcp-1, Tp63, c-cpn, p63
Gene
UniProtKB-ID: TCPA_MOUSE
UniprotKB: P11983
UniParc: UPI00014F7AFD, UPI000000185C
EMBL: AK165665, AK167529, D10606, M20130, AK166966, AK166828, AK151068, S46763, M12899, BC003809, AK152641, D90344, AK153430, AK149755, AK149611, AK151445
Ensembl: ENSMUSG00000068039
KO: mmu:21454
Nucleutide sequences
EMBL-CDS: BAE30084.1, BAE39149.1, BAE38327.1, AAA40338.1, AAB23855.1, BAE39052.1, BAE39599.1, BAA14356.1, BAE31988.1, BAE28989.1, BAE29063.1, BAE30407.1, BAA01461.1, AAH03809.1, AAA40337.1, BAE31381.1
Ensembl_TRS: ENSMUST00000089024, ENSMUST00000151287
Protein sequencees
Ensembl_PRO: ENSMUSP00000086418, ENSMUSP00000116108
RefSeq: NP_038714.2, NP_001277641.1
Others
UniRef100: UniRef100_P11983
UniRef90: UniRef90_P11983
UniRef50: UniRef50_P17987
UniGene: Mm.229342
CCDS: CCDS28397.1, CCDS70760.1

全选

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