| Type | Description |
|---|---|
| Definition | treacle ribosome biogenesis factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-02-04 12:25:00 | Role of Tcof1 in normal embryonic development, the correlation between genetic and environmental factors on the severity of craniofacial abnormalities, and the prospect for prenatal prevention of craniofacial anomalies. [review] | 27481486 |
| 2013-08-31 12:09:00 | Tcof1 acts as a modifier of Pax3 during enteric nervous system development. | 23283078 |
| 2012-11-24 11:21:00 | identified Tcof1 as an important regulator of vagal neural crest cells (NCC) development and enteric nervous system formation; Tcof1 loss-of-function results in a deficiency of vagal NCC and their delayed colonization of the gut during early embryogenesis, which mimics the early stages of Hirschsprung's disease | 22228097 |
| 2012-09-08 11:48:00 | our research has therefore identified Treacle and as novel in vivo regulators of spindle fidelity, mitotic progression, and proliferation in the maintenance and localization of neural progenitor cells. | 22479190 |
| 2010-09-20 11:28:00 | Loss-of-function mutation in Tcof1 results in defects in middle ear postnatal development and conductive hearing loss. | 20106873 |
| Type | IDs |
|---|---|
| Synonymous | AA408847, AW209012, treacle |
| Gene |
UniProtKB-ID:
TCOF_MOUSE,
H3BL37_MOUSE,
Q6PFZ6_MOUSE
UniprotKB:
O08784,
H3BL37,
Q6PFZ6
UniParc:
UPI000035588D,
UPI00001CDEB5,
UPI0000027AAC
EMBL:
BC057342,
AC139759,
U81030,
AF001794,
BC060105
Ensembl:
ENSMUSG00000024613
KO:
mmu:21453
|
| Nucleutide sequences |
EMBL-CDS:
AAB71347.1,
AAB60933.1,
AAH60105.1,
AAH57342.1
Ensembl_TRS:
ENSMUST00000176630,
ENSMUST00000175934
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000135476,
ENSMUSP00000135639
RefSeq:
NP_035682.1,
XP_011245176.1,
XP_011245177.1,
XP_006525840.1,
NP_001185913.1
|
| Others |
UniRef100:
UniRef100_O08784,
UniRef100_Q6PFZ6,
UniRef100_H3BL37
UniRef90:
UniRef90_F6R3V4,
UniRef90_O08784
UniRef50:
UniRef50_O08784,
UniRef50_Q13428-5
UniGene:
Mm.486251
CCDS:
CCDS37836.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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