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214523 Tmprss4

214523

Tmprss4

transmembrane protease, serine 4

protein-coding

Mus musculus

基因描述

Type Description
Definition transmembrane protease, serine 4

研究结论

Date Results Publications
2018-06-30 11:35:00 The lung fibrotic response evaluated at 28 days after bleomycin injury was markedly attenuated in the haplodeficient and deficient TMPRSS4 mice. 29529050
2016-05-21 12:44:00 Epithelial Sodium Channel-Mediated Sodium Transport Is Not Dependent on the Membrane-Bound CAP2/Tmprss4 26309024
2013-04-13 11:02:00 Progression and metastatic potential of several cancers is concordant with an increased expression of TMPRSS4. 22944691
2012-02-11 10:29:00 TMPRSS4 primarily activates ENaC by cleaving basic residues within the tract gammaK173-K186 distal to the furin cleavage site, thereby releasing a previously defined key inhibitory tract encompassing gammaR158-F168 from the gamma-subunit. 21993886
2010-01-21 00:00:00 mutations in conserved residues of mCAP2 located in two protein-protein interacting domains significantly modulated ENaC activation 16524950

名称对应

Type IDs
Synonymous CAP2, mCAP2
Gene
UniProtKB-ID: TMPS4_MOUSE
UniprotKB: Q8VCA5
UniParc: UPI0000028865
EMBL: BC021368, AY043240
Ensembl: ENSMUSG00000032091
KO: mmu:214523
Nucleutide sequences
EMBL-CDS: AAH21368.1, AAK85307.1
Ensembl_TRS: ENSMUST00000034599
Protein sequencees
Ensembl_PRO: ENSMUSP00000034599
RefSeq: NP_001351457.1, XP_017168761.1, NP_663378.1
Others
UniRef100: UniRef100_Q8VCA5
UniRef90: UniRef90_Q8VCA5
UniRef50: UniRef50_Q8VCA5
UniGene: Mm.436756
CCDS: CCDS40607.1

全选

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研究热度

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