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2145 EZH1

2145

EZH1

enhancer of zeste 1 polycomb repressive complex 2 subunit

protein-coding

Homo sapiens

基因描述

Type Description
Definition enhancer of zeste 1 polycomb repressive complex 2 subunit

研究结论

Date Results Publications
2021-02-20 13:33:00 Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction. 33514705
2020-09-26 13:08:00 Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas. 31747604
2020-03-14 10:50:00 Findings highlight the role of EZH1 in non-histone lysine methylation, indicating that cooperation between AML1-ETO and EZH1 and AML1-ETO site-specific lysine methylation promote AML1-ETO transcriptional repression in leukemia. 31699991
2019-10-26 10:43:00 EZH1 mutations predominantly occurred in clinically benign follicular neoplasms without RAS mutations. 29723601
2019-06-01 13:17:00 functions mostly within canonical PRC2 and exhibits proliferation-dependent redundancy that shapes mutational signatures in cancer 30867289

名称对应

Type IDs
Synonymous KMT6B
Gene
UniProtKB-ID: EZH1_HUMAN, A0A0A0MSY9_HUMAN
UniprotKB: Q92800, A0A0A0MSY9
UniParc: UPI00018E180C, UPI00005785FE, UPI00018E180D, UPI0002840F0E, UPI00018E180E, UPI000012A3BA
EMBL: L38934, AC100793, KC877670, AK295853, AB002386, U50315, BC015882, AK304835, AK295626, AK299887, CH471152, AB004818, BT009782
Ensembl: ENSG00000108799
KO: hsa:2145
Nucleutide sequences
EMBL-CDS: BAG61734.1, BAG58503.1, BAG58659.1, AAP88784.1, AAC50778.1, EAW60870.1, AAB59574.1, AAH15882.1, BAA25019.1, BAG65579.1, BAA20842.2
Ensembl_TRS: ENST00000428826, ENST00000590078, ENST00000585893, ENST00000592743, ENST00000415827
Protein sequencees
Ensembl_PRO: ENSP00000466924, ENSP00000465220, ENSP00000467871, ENSP00000404658, ENSP00000407869
RefSeq: NP_001308010.1, NP_001982.2, NP_001308008.1, XP_005257202.1, XP_016879839.1, XP_016879841.1, XP_011522819.1, NP_001308011.1, XP_016879840.1
Others
UniRef100: UniRef100_A0A0A0MSY9, UniRef100_Q92800
UniRef90: UniRef90_Q92800
UniRef50: UniRef50_Q15910
UniGene: Hs.194669
CCDS: CCDS82129.1, CCDS32659.1

全选

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研究热度

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