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21432 Tcl1

21432

Tcl1

T cell lymphoma breakpoint 1

protein-coding

Mus musculus

基因描述

Type Description
Definition T cell lymphoma breakpoint 1

研究结论

Date Results Publications
2021-02-06 13:56:00 Protein kinase Akt2/PKBbeta is involved in blastomere proliferation of preimplantation mouse embryos. 31552693
2020-11-21 13:28:00 TCL1 transgenic mice as a model for CD49d-high chronic lymphocytic leukemia. 32086446
2018-03-17 12:10:00 acalabrutinib showed increased BTK selectivity compared with ibrutinib while demonstrating significant antitumor efficacy in vivo on par with ibrutinib. Similarly, in the TCL1 adoptive transfer model, decreased phosphorylation of BTK, PLCgamma2, and S6 was observed. Most notably, treatment with acalabrutinib resulted in a significant increase in survival compared with mice receiving vehicle 27903679
2018-03-10 10:30:00 suggests that in the TCL1-tg mouse, main tumor support may not be derived from CD4+ T cells, but from the monocytic population 26522084
2017-11-26 01:40:00 we revealed that one of the key functions of KLF4-induced TCL1 during reprogramming is to promote the metabolic shift from oxidative phosphorylation to glycolysis. 28262547

名称对应

Type IDs
Synonymous Tcl1a
Gene
UniProtKB-ID: TCL1A_MOUSE, Q3UES7_MOUSE, H3BJP6_MOUSE
UniprotKB: P56280, Q3UES7, H3BJP6
UniParc: UPI0000027634, UPI00005AC888, UPI00024675A0
EMBL: Y15376, BC052336, AC124777, AF031956, AK149361
Ensembl: ENSMUSG00000041359
KO: mmu:21432
Nucleutide sequences
EMBL-CDS: AAH52336.1, AAB87461.1, CAA75599.1, BAE28834.1
Ensembl_TRS: ENSMUST00000041316, ENSMUST00000101071, ENSMUST00000176579
Protein sequencees
Ensembl_PRO: ENSMUSP00000036066, ENSMUSP00000098632, ENSMUSP00000135069
RefSeq: NP_033363.1, NP_001276397.1, NP_001296413.1, NP_001296414.1
Others
UniRef100: UniRef100_P56280, UniRef100_Q3UES7, UniRef100_H3BJP6
UniRef90: UniRef90_Q3UES7, UniRef90_H3BJP6, UniRef90_P56280
UniRef50: UniRef50_P56280, UniRef50_Q3UES7, UniRef50_H3BJP6
UniGene: Mm.18154
CCDS: CCDS36549.1

全选

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