| Type | Description |
|---|---|
| Definition | upstream binding transcription factor, RNA polymerase I |
| Date | Results | Publications |
|---|---|---|
| 2017-02-18 10:21:00 | UBF and Nopp140 dynamic redistribution between the two-cell and blastocyst stages (time of implantation) is correlated with morphological and structural modifications that occur in embryonic nucleolar compartments. | 26984997 |
| 2016-08-20 10:47:00 | inhibition of UBF function is a major factor in the cytotoxicity of cisplatin; its depletion selectively induces p53-independent apoptotic death in transformed cells | 26317157 |
| 2015-11-21 11:16:00 | Loss of UBF also unexpectedly induced the formation in cells of a large sub-nuclear structure resembling the nucleolar precursor body (NPB) of oocytes and early embryos. | 25121932 |
| 2015-09-26 13:16:00 | we have uncovered a novel role for UBTF1 and UBTF2 in maintaining genome stability through coordinating the expression of highly transcribed Pol I (UBTF1 activity) and Pol II genes (UBTF2 activity). | 25452314 |
| 2013-11-30 11:58:00 | Inhibition of the POL1 pathway delays and suppresses the development of experimental autoimmune encephalomyelitis and ameliorates the disease in mice with persistent clinical signs. | 23998422 |
| Type | IDs |
|---|---|
| Synonymous | A930005G04Rik, NOR-90, Tcfubf, UBF, UBF-1, UBF1 |
| Gene |
UniProtKB-ID:
A2AWT7_MOUSE,
A2AWT6_MOUSE,
Q9DBH1_MOUSE,
A2AWT5_MOUSE
UniprotKB:
A2AWT7,
A2AWT6,
Q9DBH1,
A2AWT5
UniParc:
UPI000024D950,
UPI00003540DD,
UPI0000028311,
UPI000024D951
EMBL:
AL954730,
AK004961
Ensembl:
ENSMUSG00000020923
KO:
mmu:21429
|
| Nucleutide sequences |
EMBL-CDS:
BAB23701.1
Ensembl_TRS:
ENSMUST00000006754,
ENSMUST00000178839,
ENSMUST00000107115,
ENSMUST00000107117,
ENSMUST00000107119,
ENSMUST00000079589,
ENSMUST00000107123,
ENSMUST00000173870,
ENSMUST00000174302
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000006754,
ENSMUSP00000102736,
ENSMUSP00000102732,
ENSMUSP00000102734,
ENSMUSP00000136310,
ENSMUSP00000133844,
ENSMUSP00000078539,
ENSMUSP00000133611,
ENSMUSP00000102740
RefSeq:
XP_017169919.1,
XP_036012403.1,
NP_001349480.1,
NP_001349476.1,
NP_001349481.1,
NP_001349477.1,
NP_001037848.1,
XP_030101638.1,
NP_001349479.1,
NP_001349474.1,
NP_035681.2,
NP_001289883.1,
NP_001349478.1,
XP_011247190.1,
XP_030101637.1,
NP_001289884.1,
NP_001349473.1
|
| Others |
UniRef100:
UniRef100_A2AWT7,
UniRef100_A2AWT6,
UniRef100_A2AWT5,
UniRef100_Q9DBH1
UniRef90:
UniRef90_A2AWT6,
UniRef90_A2AWT5,
UniRef90_Q9DBH1
UniRef50:
UniRef50_P17480-2,
UniRef50_P17480,
UniRef50_A0A452SGW8
UniGene:
Mm.2845
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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