| Type | Description |
|---|---|
| Definition | transcription factor 7 like 1 (T cell specific, HMG box) |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:09:00 | beta-catenin stimulates Tcf7l1 degradation through recruitment of casein kinase 2 in mouse embryonic stem cells. | 31987502 |
| 2019-03-16 12:46:00 | Tcf7l1 directly regulates cardiomyocyte differentiation in embryonic stem cells. | 30326964 |
| 2019-03-13 08:38:00 | Telomeric noncoding RNA maintains the pluripotency of murine embryonic stem cells serving as a responding mediator to the Wnt/beta-catenin signaling changes, eventually modulating the expression of TCF3, a well-established primary repressor for mESC stemness. | 29513567 |
| 2017-09-09 10:45:00 | Tcf7l1 defines the border between the neural crest and the prospective forebrain via restriction of the Wnt/beta-catenin signaling gradient. | 27302397 |
| 2016-08-20 10:26:00 | report the identification of two independent missense variants in human TCF7L1, p.R92P and p.R400Q, in a cohort of patients with forebrain and/or pituitary defects | 26764381 |
| Type | IDs |
|---|---|
| Synonymous | Tcf-3, Tcf3, bHLHb21 |
| Gene |
UniProtKB-ID:
TF7L1_MOUSE,
A1A550_MOUSE,
A1A549_MOUSE
UniprotKB:
Q9Z1J1,
A1A550,
A1A549
UniParc:
UPI000002334D,
UPI0000136847,
UPI0000EA331C
EMBL:
AF057691,
AC125039,
BC128306,
AJ223233,
AC153613,
AJ223069,
BC128305
Ensembl:
ENSMUSG00000055799
KO:
mmu:21415
|
| Nucleutide sequences |
EMBL-CDS:
CAA11201.1,
CAA11070.1,
AAC13696.1,
AAI28307.1,
AAI28306.1
Ensembl_TRS:
ENSMUST00000069536,
ENSMUST00000114053
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000069403,
ENSMUSP00000109687
RefSeq:
NP_001073290.1,
XP_006505945.1,
NP_033358.2
|
| Others |
UniRef100:
UniRef100_Q9Z1J1,
UniRef100_A1A549,
UniRef100_A1A550
UniRef90:
UniRef90_Q9Z1J1,
UniRef90_A1A549
UniRef50:
UniRef50_F1MJS2,
UniRef50_Q9Z1J1
UniGene:
Mm.440067
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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