| Type | Description |
|---|---|
| Definition | transcription factor 21 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:11:00 | A Deactivation Factor of Fibrogenic Hepatic Stellate Cells Induces Regression of Liver Fibrosis in Mice. | 31549421 |
| 2020-02-22 11:23:00 | After E15.5, Tcf21 progenitor cells exclusively become lipofibroblasts and interstitial fibroblasts. Lipid metabolism genes were highly expressed in perinatal and adult Tcf21 lineage cells. Overexpression of Tcf21 in primary neonatal lung fibroblasts led to increases in intracellular neutral lipids, suggesting a regulatory role for Tcf21 in lipofibroblast function. | 30675802 |
| 2019-09-07 12:25:00 | findings indicate that Tcf21 has distinct roles in the cap mesenchyme and stromal mesenchyme compartments during kidney development and suggest that Tcf21 regulates key molecular pathways required for branching morphogenesis | 30377232 |
| 2019-07-06 10:51:00 | Upon high fat diet exposure, PKR1 (tcf-/-) mice displayed excessive fat deposition in the atrioventricular groove, perivascular area, and pericardium, which was accompanied by an impaired vascular network and cardiac dysfunction. | 29038558 |
| 2018-12-29 10:29:00 | These results suggest that TCF21 contributes to the proinflammatory environment in VIS fat depots and to active ECM remodeling of these depots by regulating IL6 expression and MMP-dependent ECM remodeling in a spatiotemporally coordinated manner. | 29540474 |
| Type | IDs |
|---|---|
| Synonymous | Pod-1, Pod1, bHLHa23, capsulin, epc, epicardin |
| Gene |
UniProtKB-ID:
TCF21_MOUSE
UniprotKB:
O35437
UniParc:
UPI00000217D1
EMBL:
AF035717,
BC053525,
AK135423,
AF029753,
AF047418,
AK011575,
AK157289,
AB009453,
AF036945
Ensembl:
ENSMUSG00000045680
KO:
mmu:21412
|
| Nucleutide sequences |
EMBL-CDS:
AAB84256.1,
AAC23537.1,
BAE34032.1,
BAA23883.1,
AAC62531.1,
BAE22527.1,
AAH53525.1,
BAB27709.1,
AAC62513.1
Ensembl_TRS:
ENSMUST00000049930
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000053178
RefSeq:
NP_035675.1
|
| Others |
UniRef100:
UniRef100_O35437
UniRef90:
UniRef90_O35437
UniRef50:
UniRef50_O35437
UniGene:
Mm.16497
CCDS:
CCDS23732.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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