| Type | Description |
|---|---|
| Definition | S-phase kinase-associated protein 1A |
| Date | Results | Publications |
|---|---|---|
| 2020-04-06 08:32:00 | SKP1 localizes to synapsed chromosome axes and evicts HORMAD proteins from these regions in meiotic spermatocytes. SKP1 maintains synapsis in meiosis of both sexes. SKP1-deficient spermatocytes display premature desynapsis, precocious pachytene exit, loss of PLK1 and BUB1 at centromeres. SKP1-deficient spermatocytes show sharply reduced MPF activity and fail to enter MI despite treatment with okadaic acid. | 32232159 |
| 2017-11-26 00:01:00 | Consistent with Skp1a functioning through regulation of Nmnat2, Skp1a knockdown fails to protect axons from Nmnat2 knockdown. | 27732853 |
| 2017-06-24 13:00:00 | Lysine 29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response. | 27063938 |
| 2014-01-25 11:10:00 | Substrate binding promotes formation of the Skp1-Cul1-Fbxl3 (SCF(Fbxl3)) protein complex. | 24085301 |
| 2012-09-01 10:41:00 | In this review, deficiency of SKP1A in SN4741 cells closely recapitulates cardinal features of the dopamine (DA) neuron pathology of human Parkinson's disease, such as decreased expression of DA phenotypic markers and cell cycle aberrations. | 22166427 |
| Type | IDs |
|---|---|
| Synonymous | 15kDa, 2610043E24Rik, 2610206H23Rik, EMC19, OCP-II, OCP2, SKP1, Tceb1l, p19A, p19Skp1 |
| Gene |
UniProtKB-ID:
SKP1_MOUSE,
Q5SUR3_MOUSE
UniprotKB:
Q9WTX5,
Q5SUR3
UniParc:
UPI00000242DE
EMBL:
AK088339,
AK014245,
AK027909,
AK010628,
AK012498,
AK002983,
BC002115,
AK078330,
AF083214,
AK160198,
AK152609
Ensembl:
ENSMUSG00000036309
KO:
mmu:21402
|
| Nucleutide sequences |
EMBL-CDS:
BAC25660.1,
BAC37220.1,
BAB22496.1,
BAC40292.1,
BAB27074.1,
AAH02115.1,
BAB29222.1,
BAB28281.1,
AAD16036.1,
BAE35688.1,
BAE31355.1
Ensembl_TRS:
ENSMUST00000037324,
ENSMUST00000109072
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000038744,
ENSMUSP00000104700
RefSeq:
XP_006532849.1,
XP_036012398.1,
NP_035673.3
|
| Others |
UniRef100:
UniRef100_Q9WTX5
UniRef90:
UniRef90_P63208
UniRef50:
UniRef50_P63208
UniGene:
Mm.42944
CCDS:
CCDS24669.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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