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2140 EYA3

2140

EYA3

EYA transcriptional coactivator and phosphatase 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition EYA transcriptional coactivator and phosphatase 3

研究结论

Date Results Publications
2020-05-02 12:31:00 These findings suggest that EYA3's tyrosine phosphorylation sites are non-equivalent with their phosphorylation levels being under the control of Src-kinase activity and of EYA3's autodephosphorylation. 31847183
2019-09-14 10:06:00 WDR1 is an EYA3-specific substrate, which implies that EYA3 is a key modulator of the cytoskeletal reorganization 29440662
2018-04-21 10:43:00 Study identifies Eya3 as a regulator of PP2A, a major cellular Ser/Thr phosphatase, and uncovers a mechanism of controlling the stability of a critical oncogene, c-Myc. 29535359
2014-08-09 11:01:00 Benzbromarone metabolites and derivatives function as EYA3 inhibitory anti-angiogenic agents. 24367676
2013-04-06 13:03:00 These studies identify EYA3 as a novel mediator of chemoresistance in Ewing sarcoma and define the molecular mechanisms of both EYA3 overexpression and of EYA3-mediated chemoresistance 22723308

名称对应

Type IDs
Gene
UniProtKB-ID: EYA3_HUMAN
UniprotKB: Q99504
UniParc: UPI000015FFE5, UPI00000745A1, UPI0000E1E76B, UPI0000E59271, UPI0001A51B9B
EMBL: CH471059, AJ007991, AK289805, AK298129, Y10262, AL512288, BC041667, U81602, AL137792, AK295745
Ensembl: ENSG00000158161
KO: hsa:2140
Nucleutide sequences
EMBL-CDS: BAF82494.1, EAX07714.1, AAB42066.1, BAG60409.1, BAG58579.1, CAA07814.1, EAX07713.1, AAH41667.1, CAA71311.1
Ensembl_TRS: ENST00000373863, ENST00000540618, ENST00000436342, ENST00000373871
Protein sequencees
Ensembl_PRO: ENSP00000405587, ENSP00000362978, ENSP00000442558, ENSP00000362970
RefSeq: NP_001269489.1, XP_024309782.1, NP_001269490.1, XP_024309755.1, NP_001981.2, XP_006710512.1, XP_024309763.1, XP_011539303.1, XP_011539305.1, XP_011539306.1, XP_024309781.1, NP_001269491.1, XP_011539301.1
Others
UniRef100: UniRef100_Q99504
UniRef90: UniRef90_Q99504
UniRef50: UniRef50_Q99504
UniGene: Hs.185774
CCDS: CCDS60051.1, CCDS60050.1, CCDS60052.1, CCDS316.1

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