| Type | Description |
|---|---|
| Definition | titin-cap |
| Date | Results | Publications |
|---|---|---|
| 2014-03-22 11:42:00 | cardiac telethonin is constitutively bis-phosphorylated and suggest that such phosphorylation is critical for normal telethonin function, which may include maintenance of transverse tubule organization and intracellular Ca(2+) transients. | 24280220 |
| 2013-06-22 10:04:00 | Tcap is a critical, load-sensitive regulator of t-tubule structure and function. | 23100327 |
| 2011-11-12 10:55:00 | Telethonin knockout mice develop heart failure following biomechanical stress, owing at least in part to apoptosis of cardiomyocytes, an effect that may also play a role in human heart failure. | 21799151 |
| 2011-05-21 10:10:00 | Whereas both promotor E boxes in Tcap are required for full activation by MyoD or myogenin in NIH3T3 cells, the promoter proximal E box has a greater contribution to activation in C2C12 cells and to activation by MyoD in NIH3T3 cells. | 21305318 |
| 2010-01-21 00:00:00 | Findings suggest that TCAP knockdown with RNA interference alters normal muscle cell differentiation. | 18440815 |
| Type | IDs |
|---|---|
| Synonymous | AI503981, AJ223855 |
| Gene |
UniProtKB-ID:
TELT_MOUSE,
Q545G3_MOUSE
UniprotKB:
O70548,
Q545G3
UniParc:
UPI0000001A46
EMBL:
Y15845,
AJ223854,
AK010167,
BC027631
Ensembl:
ENSMUSG00000007877
KO:
mmu:21393
|
| Nucleutide sequences |
EMBL-CDS:
AAH27631.1,
CAB38077.1,
CAA11585.1,
BAB26743.1
Ensembl_TRS:
ENSMUST00000008021
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000008021
RefSeq:
NP_035670.2
|
| Others |
UniRef100:
UniRef100_O70548
UniRef90:
UniRef90_O70548
UniRef50:
UniRef50_O70548
UniGene:
Mm.10762
CCDS:
CCDS25346.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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