| Type | Description |
|---|---|
| Definition | EYA transcriptional coactivator and phosphatase 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-21 11:24:00 | The inhibition of AKT attenuated EYA2-induced Bcl-2 upregulation. In conclusion, our data demonstrated that Eya2 was upregulated in prostate cancers. EYA2 promotes cell proliferation and invasion as well as cancer progression by regulating docetaxel sensitivity and mitochondrial membrane potential, possibly via the AKT/Bcl-2 axis. | 31317026 |
| 2019-06-22 12:45:00 | study revealed that miR-219a-5p function as tumour suppressor regulates osteosarcoma cell invasiveness by repressing EYA2 expression. | 30449183 |
| 2018-06-02 11:43:00 | our data indicate that Eya2 may serve as a potential oncoprotein in human astrocytoma. Eya2 regulates astrocytoma cell proliferation and invasion, possibly through the regulation of ERK signaling. | 28901379 |
| 2018-05-19 10:28:00 | EYA2 knockdown led to decreased metastatic spread of breast cancer cells to the lung and greatly attenuated the ability of EGFR to regulate the epithelial-to-mesenchymal transition markers. | 28703807 |
| 2017-09-16 11:57:00 | High EYA2 expression is associated with acute myeloid leukemia. | 28416638 |
| Type | IDs |
|---|---|
| Synonymous | EAB1 |
| Gene |
UniProtKB-ID:
EYA2_HUMAN,
E7ETN2_HUMAN
UniprotKB:
O00167,
E7ETN2
UniParc:
UPI000012A3B4,
UPI000002A938,
UPI00015DF89F,
UPI000002A939
EMBL:
Y10261,
BT006682,
U81601,
AL359434,
BC008803,
AL354766,
KF456926,
BC000289,
AL121776,
BC013882,
AL049540,
AJ007992,
KF456925,
U71207,
AL022342
Ensembl:
ENSG00000064655
KO:
hsa:2139
|
| Nucleutide sequences |
EMBL-CDS:
AAB51120.1,
AAB42065.1,
AAH00289.2,
CAI23166.1,
AAH08803.1,
CAA07815.1,
AAH13882.2,
AAP35328.1,
CAA71310.1
Ensembl_TRS:
ENST00000497062,
ENST00000357410,
ENST00000327619,
ENST00000611592,
ENST00000317304
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000333640,
ENSP00000417105,
ENSP00000349986,
ENSP00000321590,
ENSP00000483392
RefSeq:
XP_016883210.1,
XP_005260384.1,
NP_005235.3,
NP_742108.2
|
| Others |
UniRef100:
UniRef100_O00167,
UniRef100_E7ETN2
UniRef90:
UniRef90_O00167,
UniRef90_O00167-2
UniRef50:
UniRef50_O00167,
UniRef50_O00167-2
UniGene:
Hs.472877,
Hs.722040,
Hs.722415,
Hs.722416
CCDS:
CCDS13403.1,
CCDS54471.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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