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21389 Tbx6

21389

Tbx6

T-box 6

protein-coding

Mus musculus

基因描述

Type Description
Definition T-box 6

研究结论

Date Results Publications
2020-07-11 11:19:00 Tbx6 promotes cardiomyocyte proliferation in postnatal and adult mouse hearts by modifying the expression of cell cycle regulators. 31010673
2019-10-05 11:10:00 The prolonged Tbx6 expression suppressed cardiac differentiation and induced somite lineages, including skeletal muscle and chondrocytes. Thus, Tbx6 is critical for mesoderm induction and subsequent lineage diversification. 30100166
2019-06-22 10:38:00 our findings in the newly collected human Congenital vertebral malformations (CVMs) subjects and Tbx6 mouse models consistently support the contention that TBX6 compound inheritance causes CVMs, potentially via a gene dosage-dependent mechanism. 30307510
2019-05-11 10:24:00 In Tbx6 null mutant embryos intermediate mesoderm formation is severely compromised. 30548789
2019-05-04 10:18:00 The authors succeeded in reproducing in vivo events using a mouse embryonic stem cell induction system, in which Tbx6 degradation occurred via Ripply2. 29761784

名称对应

Type IDs
Synonymous rv
Gene
UniProtKB-ID: TBX6_MOUSE
UniprotKB: P70327
UniParc: UPI0001F78C25, UPI0000194FA0
EMBL: BC140951, AY654733, U57331
Ensembl: ENSMUSG00000030699
KO: mmu:21389
Nucleutide sequences
EMBL-CDS: AAI40952.1, AAC53110.1, AAT72924.1
Ensembl_TRS: ENSMUST00000172352, ENSMUST00000094037
Protein sequencees
Ensembl_PRO: ENSMUSP00000091579, ENSMUSP00000126418
RefSeq: NP_035668.2
Others
UniRef100: UniRef100_P70327
UniRef90: UniRef90_P70327
UniRef50: UniRef50_O95947
UniGene: Mm.727
CCDS: CCDS21843.1

全选

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研究热度

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