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21375 Tbr1

21375

Tbr1

T-box brain gene 1

protein-coding

Mus musculus

基因描述

Type Description
Definition T-box brain gene 1

研究结论

Date Results Publications
2020-06-20 12:25:00 Tbr1 is genetically ablated during retinal development, these two RGC groups cannot develop. Ectopically expressing Tbr1 in M4 ipRGCs during development alters dendritic branching and density but not the inner plexiform layer stratification level. 30995485
2019-08-17 12:15:00 Tbr1 gene dosage regulates neocortex layer 6 connectivity. 30318412
2019-05-18 10:59:00 Two transmembrane molecules, Sorcs3 and Cdh8, act as effectors of the Tbr1-controlled lamination program 29632360
2019-04-13 11:09:00 Tbr1 haploinsufficiency specifically impaired olfactory discrimination but not olfactory sensation. Tbr1+/- mice exhibited abnormal olfactory bulbs. 30792833
2018-01-20 10:08:00 Study induced neuronal differentiation of mouse bone mesenchymal stem cells (bMSCs) into neuron-like cells in vitro. miR-122-5p was well complementary with the target site of Tbr1 mRNA3'UTR and could inhibit Tbr1 expression by binding to its 3'UTR. Expressions of Tbr1 mRNA and protein were decreased. Overexpression of miR-122-5p downregulated the expressions of Tbr1, NSE, and TAU. 28240720

名称对应

Type IDs
Gene
UniProtKB-ID: TBR1_MOUSE
UniprotKB: Q64336
UniParc: UPI000019B09A
EMBL: CH466519, BC052737, U49251, AL845291, BC058399
Ensembl: ENSMUSG00000035033
KO: mmu:21375
Nucleutide sequences
EMBL-CDS: AAA92011.1, AAH52737.1, AAH58399.1, EDL26982.1
Ensembl_TRS: ENSMUST00000048934
Protein sequencees
Ensembl_PRO: ENSMUSP00000046787
RefSeq: XP_006499161.1, NP_033348.2, XP_036016131.1, XP_036016132.1
Others
UniRef100: UniRef100_Q64336
UniRef90: UniRef90_Q64336
UniRef50: UniRef50_Q16650
UniGene: Mm.308525, Mm.404741
CCDS: CCDS16063.1

全选

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研究热度

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