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21354 Tap1

21354

Tap1

transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)

protein-coding

Mus musculus

基因描述

Type Description
Definition transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)

研究结论

Date Results Publications
2016-07-16 11:13:00 TAP-independent self-peptides enhance T cell recognition of immune-escaped tumors. 26784543
2014-03-29 10:08:00 It transport class I antigens to cell surface of CD8 positive lymphocytes which have a vital role in liver inflammation like fructose-induced steatosis. 23488792
2014-02-22 10:47:00 Knocking out Tap1 abolishes NMDAR-dependent LTD in area CA1 of adult mouse hippocampus and is accompanied by memory deficits. MHC class I expression could be an unexpected cause of disrupted synaptic plasticity and cognitive deficits. 23959708
2012-11-24 11:18:00 Apoe(-/-)Tap1(-/-) mice develop atherosclerosis equal to Apoe(-/-) mice, indicating a minor role for CD8(+) T cells and TAP1-dependent antigen presentation in the disease process. 22479479
2012-05-19 11:43:00 Role of metalloproteases in vaccinia virus epitope processing for transporter associated with antigen processing (TAP)-independent human leukocyte antigen (HLA)-B7 class I antigen presentation. 22298786

名称对应

Type IDs
Synonymous ABC17, APT1, Abcb2, Ham-1, Ham1, MTP1, PSF1, RING4, TAP, Tap-1, Y3
Gene
UniProtKB-ID: TAP1_MOUSE, Q3U6V4_MOUSE, Q3TBA3_MOUSE
UniprotKB: P21958, Q3U6V4, Q3TBA3
UniParc: UPI000002529C, UPI00005B27B5, UPI00005ACC57
EMBL: U60018, CH466660, AK152953, CR974422, M55637, U60019, X59615, AK162731, AF027865, AK171363
Ensembl: ENSMUSG00000037321
KO: mmu:21354
Nucleutide sequences
EMBL-CDS: AAB41963.1, AAB41962.1, AAB81534.1, BAE37041.1, AAA39570.1, CAA42178.1, EDL10260.1, BAE31620.1, BAE42411.1
Ensembl_TRS: ENSMUST00000170086, ENSMUST00000041633
Protein sequencees
Ensembl_PRO: ENSMUSP00000128401, ENSMUSP00000039264
RefSeq: NP_038711.2, NP_001155202.1
Others
UniRef100: UniRef100_P21958, UniRef100_Q3TBA3, UniRef100_Q3U6V4
UniRef90: UniRef90_P21958
UniRef50: UniRef50_P36370
UniGene: Mm.482076
CCDS: CCDS28643.1

全选

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