| Type | Description |
|---|---|
| Definition | Rho guanine nucleotide exchange factor (GEF) 11 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 12:06:00 | the ablation of Esrp1 and Esrp2 impairs epithelial tight junction (TJ) integrity through loss of the epithelial isoform of Rho GTP exchange factor Arhgef11. | 30485810 |
| 2016-09-03 12:07:00 | These results demonstrate that PDZ-RhoGEF acts as a key determinant of mammalian metabolism and obesity-associated pathologies. | 26512886 |
| 2014-02-08 11:06:00 | Agonist-induced Ca2+ sensitization in smooth muscle: redundancy of Rho guanine nucleotide exchange factors (RhoGEFs) and response kinetics, a caged compound study. | 24106280 |
| 2013-06-29 12:11:00 | PDZ-RhoGEF and LARG are essential for embryonic development and provide a link between thrombin and LPA receptors and Rho activation. | 23467409 |
| 2012-09-15 10:09:00 | results suggest that ARHGEF11 mediates RhoA-myosin light chain signaling pathways at cell-cell junctions, functioning in cooperation with ZO-1 | 22665792 |
| Type | IDs |
|---|---|
| Synonymous | PDZ-RhoGEF, Prg, RhoGEF, mKIAA0380 |
| Gene |
UniProtKB-ID:
Q68FM7_MOUSE
UniprotKB:
Q68FM7
UniParc:
UPI0000419E9A
EMBL:
AC139241,
AC161454,
BC079565
Ensembl:
ENSMUSG00000041977
KO:
mmu:213498
|
| Nucleutide sequences |
EMBL-CDS:
AAH79565.1
Ensembl_TRS:
ENSMUST00000039476
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000039900
RefSeq:
XP_006501330.1,
NP_001003912.1,
XP_006501328.1,
XP_030108395.1,
XP_006501327.1,
XP_030108396.1,
XP_006501333.1,
XP_036018893.1,
XP_030108397.1,
XP_030108394.1,
XP_011238369.1,
XP_006501331.1,
XP_006501334.1,
XP_036018891.1,
XP_006501335.1,
XP_030108398.1,
XP_036018892.1,
XP_006501337.1,
NP_001347124.1,
XP_006501336.1,
XP_006501332.1,
XP_036018894.1,
NP_001347126.1,
XP_006501329.1
|
| Others |
UniRef100:
UniRef100_Q68FM7
UniRef90:
UniRef90_Q9ES67
UniRef50:
UniRef50_O15085
UniGene:
Mm.287267
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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