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21349 Tal1

21349

Tal1

T cell acute lymphocytic leukemia 1

protein-coding

Mus musculus

基因描述

Type Description
Definition T cell acute lymphocytic leukemia 1

研究结论

Date Results Publications
2020-04-25 10:50:00 The cell-type-specific regions of open chromatin pinpointed two TAL1-bound endothelial enhancers in early mouse organogenesis. 32231307
2020-02-01 11:31:00 Scl and Lyl1 share functional roles in platelet production by regulating expression of partner proteins including Gata1. This functional redundancy provides one explanation for the absence of Scl and Lyl1 mutations in inherited thrombocytopenia. 31300405
2020-01-04 11:34:00 Tal1 limits the expression of multiple E2A target genes in HSCs and controls the balance of myeloid versus T lymphocyte differentiation potential in lymphomyeloid-primed progenitors. 30962294
2019-02-23 10:12:00 Ectopic expression of the TAL1 transcription factor and Pten deletion are bona-fide cooperating events. 29151585
2019-01-19 11:33:00 Study reveals a complex pattern of gene regulation by SCL, ETO2 and RYBP. Genome-wide analyses shows locus-specific binding of ETO2 and RYBP on SCL's 778 activated and repressed genes. 30560907

名称对应

Type IDs
Synonymous Hpt, SCL/tal-1, Scl, bHLHa17, tal-1
Gene
UniProtKB-ID: TAL1_MOUSE, Q3TZH7_MOUSE
UniprotKB: P22091, Q3TZH7
UniParc: UPI0000022F98
EMBL: U01530, M59764, AK157852, BC063060
Ensembl: ENSMUSG00000028717
KO: mmu:21349
Nucleutide sequences
EMBL-CDS: AAA40097.1, AAH63060.1, AAA86937.1, BAE34231.1
Ensembl_TRS: ENSMUST00000162489, ENSMUST00000161601, ENSMUST00000030489
Protein sequencees
Ensembl_PRO: ENSMUSP00000125202, ENSMUSP00000124983, ENSMUSP00000030489
RefSeq: XP_006502979.1, XP_006502977.1, XP_006502975.1, XP_006502972.1, NP_035657.1, XP_030109242.1, XP_006502976.1, XP_006502978.1, NP_001274317.1, XP_006502973.1
Others
UniRef100: UniRef100_P22091
UniRef90: UniRef90_P22091
UniRef50: UniRef50_P22091
UniGene: Mm.439685
CCDS: CCDS18486.1

全选

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