| Type | Description |
|---|---|
| Definition | leucine-rich repeat LGI family, member 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-03-17 11:13:00 | Taken together, these results support the critical involvement of LGI3 in the cytokine network by interplaying with multiple adipokines, cytokines and signaling proteins. | 28534931 |
| 2015-12-19 12:04:00 | findings show LGI3 and TNF-alpha upregulated each other in 3T3-L1 cells; study suggests LGI3 is a pro-inflammatory adipokine and forms a positive feedback loop with TNF-alpha; propose that LGI3 is a member of adipokine network that plays regulatory roles in obesity-associated adipose tissue inflammation | 25648289 |
| 2014-02-01 12:17:00 | results suggested that LGI3 may participate in adipose tissue homeostasis by negatively regulating adiponectin | 23548727 |
| 2013-02-02 11:55:00 | Data suggest that leucine-rich glioma inactivated 3 (LGI3) may be a candidate adipokine that is perturbed in obesity and suppresses adipogenesis through its receptor, ADAM23. | 22405860 |
| 2010-10-23 10:57:00 | LGI3 interacts with Flo1 in the brain, and LGI3/Flo1 mediates APP trafficking and exosome formation in neuronal cells: reveals the details of the intracellular transport system and even the secretion pathway in the brain. | 20461023 |
| Type | IDs |
|---|---|
| Synonymous | AI841179, AW049851 |
| Gene |
UniProtKB-ID:
LGI3_MOUSE,
Q3V1R3_MOUSE
UniprotKB:
Q8K406,
Q3V1R3
UniParc:
UPI0000005765,
UPI00005AB85A
EMBL:
AK132296,
AK049831,
AY174077,
BC061460,
AF515590,
BC055315
Ensembl:
ENSMUSG00000033595
KO:
mmu:213469
|
| Nucleutide sequences |
EMBL-CDS:
AAM55219.1,
AAO19739.1,
BAC33943.1,
AAH55315.1,
AAH61460.1,
BAE21087.1
Ensembl_TRS:
ENSMUST00000047331
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000046705
RefSeq:
NP_660254.1,
XP_030103578.1
|
| Others |
UniRef100:
UniRef100_Q8K406,
UniRef100_Q3V1R3
UniRef90:
UniRef90_Q8K406
UniRef50:
UniRef50_Q8K406
UniGene:
Mm.41708
CCDS:
CCDS27255.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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