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21338 Tacr3

21338

Tacr3

tachykinin receptor 3

protein-coding

Mus musculus

基因描述

Type Description
Definition tachykinin receptor 3

研究结论

Date Results Publications
2021-01-16 15:58:00 Tacr3 in the lateral habenula differentially regulates orofacial allodynia and anxiety-like behaviors in a mouse model of trigeminal neuralgia. 32264959
2019-03-30 10:08:00 we demonstrate that in the presence of E2, NKB signaling induces LH release in a kisspeptin-independent manner through the activation of NK3R (NKB receptor) neurons in the posterodorsal medial amygdala (MePD). Importantly, we show that chemogenetic activation of MePD Kiss1 neurons induces LH release, however, the stimulatory action of NKB in this area is Kiss1 neuron-independent. 30565563
2018-04-14 11:47:00 Data suggest that neurokinin 3 receptor (NK3R) might be a potential target for the anti-angiogenesis therapy. 28489574
2013-11-02 11:34:00 Data suggest that activation of neurokinin 3 and kappa-opioid receptors (NK3R and KOR) excites and inhibits kisspeptin, neurokinin B (NKB), and dynorphin (KNDy neurons). 23744642
2012-04-28 10:50:00 NKB-NK3R signaling plays a role in pubertal maturation; its alterations may contribute to pubertal disorders linked to metabolic stress and negative energy balance. 22396413

名称对应

Type IDs
Synonymous Nk3r, Nkr, Tac3r
Gene
UniProtKB-ID: NK3R_MOUSE
UniprotKB: P47937
UniParc: UPI0000022DEF
EMBL: X87823, AK031898, AF233341, AK046424, L27827
Ensembl: ENSMUSG00000028172
KO: mmu:21338
Nucleutide sequences
EMBL-CDS: CAA61088.1, AAF62517.1, BAC27596.1, AAA17893.1, BAC32723.1
Ensembl_TRS: ENSMUST00000029822
Protein sequencees
Ensembl_PRO: ENSMUSP00000029822
RefSeq: NP_067357.1
Others
UniRef100: UniRef100_P47937
UniRef90: UniRef90_P16177
UniRef50: UniRef50_P16177
UniGene: Mm.103810
CCDS: CCDS17852.1

全选

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