Type | Description |
---|---|
Definition | frequently rearranged in advanced T cell lymphomas 2 |
Date | Results | Publications |
---|---|---|
2020-04-11 12:53:00 | TMEM98 reduces FRAT2 protein levels and, accordingly, inhibits the FRAT2-mediated induction of ss-catenin/TCF signalling. | 31961879 |
2013-04-13 11:33:00 | Data show that MLL fusion oncogenes maintain leukemia-associated Rac GTPases activity by regulating Frat gene expression, specifically Frat2. | 23074275 |
2010-02-08 11:50:00 | Data show that that Frat synergizes with Diversin in the activation of JNK/AP-1 signaling. | 19802005 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
FRAT2_MOUSE
UniprotKB:
Q8K025
UniParc:
UPI0000027FAB
EMBL:
AY518895,
BC085510,
AK081171,
BC034214
Ensembl:
ENSMUSG00000047604
KO:
mmu:212398
|
Nucleutide sequences |
EMBL-CDS:
AAH85510.1,
BAC38155.1,
AAR99812.1,
AAH34214.1
Ensembl_TRS:
ENSMUST00000059231
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000052788
RefSeq:
NP_808271.1
|
Others |
UniRef100:
UniRef100_Q8K025
UniRef90:
UniRef90_Q8K025
UniRef50:
UniRef50_P70339
UniGene:
Mm.222723
CCDS:
CCDS29813.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
31961879 |
TMEM98 is a negative regulator of FRAT mediated Wnt/Ã-catenin signalling. PLoS ONE Tanne van der Wal , Jan-Paul Lambooij , Renée van Amerongen |
2020-01-01 | - |
24952961 |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron Carol L Thompson , Lydia Ng , Vilas Menon , Salvador Martinez , Chang-Kyu Lee , Katie Glattfelder , Susan M Sunkin , Alex Henry , Christopher Lau , Chinh Dang , Raquel Garcia-Lopez , Almudena Martinez-Ferre , Ana Pombero , John L R Rubenstein , Wayne B Wakeman , John Hohmann , Nick Dee , Andrew J Sodt , Rob Young , Kimberly Smith , Thuc-Nghi Nguyen , Jolene Kidney , Leonard Kuan , Andreas Jeromin , Ajamete Kaykas , Jeremy Miller , Damon Page , Geri Orta , Amy Bernard , Zackery Riley , Simon Smith , Paul Wohnoutka , Michael J Hawrylycz , Luis Puelles , Allan R Jones |
2014-07-16 | - |
23074275 |
Frat2 mediates the oncogenic activation of Rac by MLL fusions. Blood Vanessa Walf-Vorderwülbecke , Jasper de Boer , Sarah J Horton , Renée van Amerongen , Natalie Proost , Anton Berns , Owen Williams |
2012-12-06 | - |
22064483 |
Mol. Cell. Biol. Matthew Bechard , Robert Trost , Amar M Singh , Stephen Dalton |
2012-01-01 |
Frat1,
Frat2,
Peg12,
Gsk3b
|
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
19802005 |
Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways. Oncogene R van Amerongen , M C Nawijn , J-P Lambooij , N Proost , J Jonkers , A Berns |
2010-01-07 |
Dvl2,
Frat1,
Jun,
Frat2,
Mapk8,
MAPK8
|
18973680 |
BMC Genomics Owen J Tamplin , Doris Kinzel , Brian J Cox , Christine E Bell , Janet Rossant , Heiko Lickert |
2008-01-01 |
Rnaset2a,
Ildr2,
2810410L24Rik,
Pifo,
Trrap,
Plekha1,
Cd276,
Phldb1,
6330403K07Rik,
Txndc5,
Unc119b,
Otub1,
Napg,
Cald1,
Pygb,
Pygl,
Hspa13,
Rpl31,
Acvr2b,
Agtrap,
Ank3,
Anxa5,
Ap4s1,
App,
Arg1,
Astn1,
Atm,
Bcl2l2,
Fabp7,
Hyou1,
Pdia4,
Cbx3,
Cd24a,
Cd59a,
Cdkn1c,
Cdx1,
Cldn4,
Cnn2,
Col1a1,
Hapln1,
Csnk2a1,
Cyb561,
Cyp51,
Dbt,
Mapre1,
Esd,
Amz2,
Colec12,
Fgfr2,
Fjx1,
Foxd4,
Flt4,
Fstl1,
Gal,
Galnt1,
Galt,
Gas5,
Nr6a1,
Gna14,
Gng10,
Gpc3,
Lpar1,
Gpx2,
Gsta4,
Gstm5,
Hdgf,
Hmgb1,
Foxa1,
Foxa2,
Hnrnpab,
Hoxa1,
Hpn,
Prmt1,
Sdc2,
Igfbp3,
Igfbp5,
Inpp1,
Itch,
Itga3,
Stt3a,
Khsrp,
Mxd3,
Cd99l2,
Mfap2,
Mdk,
Meis1,
Mest,
Kitl,
Mlf1,
Mvk,
Myef2,
Myl4,
Myl7,
Myl1,
Nnat,
Pabpc1,
Pak1,
Pcolce,
Pcsk5
|
16602821 |
PLoS Biol Susan Magdaleno , Patricia Jensen , Craig L Brumwell , Anna Seal , Karen Lehman , Andrew Asbury , Tony Cheung , Tommie Cornelius , Diana M Batten , Christopher Eden , Shannon M Norland , Dennis S Rice , Nilesh Dosooye , Sundeep Shakya , Perdeep Mehta , Tom Curran |
2006-04-01 | - |
16141072 |
The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C Schönbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) |
2005-09-02 | - |
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