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212139 Cc2d1a

212139

Cc2d1a

coiled-coil and C2 domain containing 1A

protein-coding

Mus musculus

基因描述

Type Description
Definition coiled-coil and C2 domain containing 1A

研究结论

Date Results Publications
2020-06-20 10:57:00 Our findings establish a critical link between elevated Rac1 activity, structural and synaptic plasticity alterations, and cognitive impairment caused by Cc2d1a deletion. 30992372
2020-04-04 11:07:00 Findings show that CC2D1A regulates cAMP intracellular signaling in a male-specific manner in the hippocampus, leading to male-specific cognitive deficits. 30732858
2018-03-10 10:27:00 Cc2d1a conditional knockout mice therefore recapitulate features of both cognitive and social impairment caused by human CC2D1A mutation 26826102
2017-12-16 11:13:00 Freud-1 is crucial for 5-HT1A autoreceptor expression and links up-regulation of 5-HT1A autoreceptors to anxiety/depression-like behavior. 29101244
2016-05-14 11:49:00 CC2D1A and CC2D1B role and function in the endocytic pathway and Notch signalling. 26720614

名称对应

Type IDs
Synonymous BC016188, Freud-1, Tape
Gene
UniProtKB-ID: C2D1A_MOUSE
UniprotKB: Q8K1A6
UniParc: UPI0000193804
EMBL: BC016188, BC027028, DQ329239
Ensembl: ENSMUSG00000036686
KO: mmu:212139
Nucleutide sequences
EMBL-CDS: AAH16188.1, ABC56419.1, AAH27028.1
Ensembl_TRS: ENSMUST00000040383
Protein sequencees
Ensembl_PRO: ENSMUSP00000046449
RefSeq: NP_001368802.1, NP_666082.2, NP_001368801.1, NP_001368800.1
Others
UniRef100: UniRef100_Q8K1A6
UniRef90: UniRef90_Q8K1A6
UniRef50: UniRef50_Q6P1N0
UniGene: Mm.41424
CCDS: CCDS40407.1

全选

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研究热度

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