| Type | Description |
|---|---|
| Definition | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-09-09 11:54:00 | these findings identify ASAP2 as a new target of Selk-dependent palmitoylation and reveal a new mechanism regulating the efficiency of FcgammaR-mediated phagocytosis. | 27601625 |
| 2017-06-24 10:31:00 | In conclusion, we have identified that ARL15 acts as an insulin-sensitizing effector molecule to upregulate the phosphorylation of members of the canonical IR/IRS1/PDPK1/AKT insulin pathway by interacting with its GAP ASAP2 and activating PDPK1. This research may provide new insights into GTPase-mediated insulin signalling regulation and facilitate the development of new pharmacotherapeutic targets for insulin sensitizati | 28322786 |
| Type | IDs |
|---|---|
| Synonymous | 6530401G17Rik, Ddef2, Gm1523, Gm592, PAG3, PAP |
| Gene |
UniProtKB-ID:
ASAP2_MOUSE,
E9PX52_MOUSE,
Q3UH27_MOUSE,
D3YX85_MOUSE
UniprotKB:
Q7SIG6,
E9PX52,
Q3UH27,
D3YX85
UniParc:
UPI00004284B1,
UPI00005AC69F,
UPI000050D1B6,
UPI00015DEB6D,
UPI00015294AE
EMBL:
AC156032,
AC153140,
AC158366,
BC096022,
BC080847,
AK147622
Ensembl:
ENSMUSG00000052632
KO:
mmu:211914
|
| Nucleutide sequences |
EMBL-CDS:
AAH80847.1,
AAH96022.1,
BAE28030.1
Ensembl_TRS:
ENSMUST00000090834,
ENSMUST00000101562,
ENSMUST00000064595,
ENSMUST00000050990
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099098,
ENSMUSP00000088344,
ENSMUSP00000063217,
ENSMUSP00000054631
RefSeq:
XP_036013194.1,
XP_030102501.1,
NP_001091637.1,
NP_001004364.2,
NP_001128664.1,
XP_036013193.1,
XP_036013195.1,
XP_006515110.1,
XP_006515111.1
|
| Others |
UniRef100:
UniRef100_Q3UH27,
UniRef100_E9PX52,
UniRef100_Q7SIG6,
UniRef100_D3YX85
UniRef90:
UniRef90_Q3UH27,
UniRef90_Q7SIG6,
UniRef90_D3YX85
UniRef50:
UniRef50_Q7SIG6,
UniRef50_O43150,
UniRef50_A0A6I8NYG7
UniGene:
Mm.358946
CCDS:
CCDS56832.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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