| Type | Description |
|---|---|
| Definition | WW, C2 and coiled-coil domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 10:57:00 | Kibra WW tandem domains bind to dendrin. Disruption of the Kibra/Dendrin interaction impairs learning and memory in mice. | 30784589 |
| 2020-03-28 11:28:00 | KIBRA inhibited CAMDI-dependent Rab11 activation, thereby attenuating AMPAR cell surface expression. | 31730661 |
| 2019-09-21 12:34:00 | KIBRA functions co-operatively with the protein tyrosine phosphatase PTPN14 to trigger mechanotransduction-regulated signals that inhibit the nuclear localization of oncogenic transcriptional co-activators YAP/TAZ. Our results argue that the selective advantage produced by 5q loss involves reduced dosage of KIBRA, promoting oncogenic functioning of YAP/TAZ in TNBC. | 29562176 |
| 2019-05-11 10:55:00 | Comparing protein profiles between KIBRA knockout and wild-type mouse brain showed significantly decreased Rab27a. Rab27a is stabilized by interacting with KIBRA, which prevents ubiquitination and degradation via the ubiquitin-proteasome pathway. | 30967557 |
| 2019-02-23 10:44:00 | Study illustrated the expression at the protein level of a memory-related protein-KIBRA in the intestine of APP/PS1 Alzheimer disease mouse model. Protein levels of KIBRA significantly increased in the jejunal myenteric plexus of APP/PS1 mice. | 29526515 |
| Type | IDs |
|---|---|
| Synonymous | AA408228, AU017197, BC037006, Kibra |
| Gene |
UniProtKB-ID:
KIBRA_MOUSE
UniprotKB:
Q5SXA9
UniParc:
UPI00001E710B
EMBL:
AL645912,
BC037006,
DQ256090,
AK220259,
BC017638,
AL596084,
BC006733
Ensembl:
ENSMUSG00000018849
KO:
mmu:211652
|
| Nucleutide sequences |
EMBL-CDS:
ABB51169.1,
AAH37006.1,
BAD90184.1,
AAH06733.1,
AAH17638.1
Ensembl_TRS:
ENSMUST00000018993
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000018993
RefSeq:
XP_030101614.1,
NP_740749.1
|
| Others |
UniRef100:
UniRef100_Q5SXA9
UniRef90:
UniRef90_Q5SXA9
UniRef50:
UniRef50_Q8IX03
UniGene:
Mm.31267
CCDS:
CCDS24545.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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