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2116 ETV2

2116

ETV2

ETS variant 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition ETS variant 2

研究结论

Date Results Publications
2021-04-03 13:32:00 FGF primes angioblast formation by inducing ETV2 and LMO2 via FGFR1/BRAF/MEK/ERK. 32910224
2020-08-22 15:29:00 ETV2/ER71 as a Therapeutic Vehicle for Cardiovascular Disease. 31534512
2020-07-25 10:29:00 These findings provide insight into the novel molecular mechanisms of ETV2 function in regulating cardiovascular lineage development from mouse embryonic stem cells. 31744543
2020-06-20 12:40:00 among the many factors wired within this complex regulatory network, ETV2, SCL and RUNX1 are the central components. All three factors are absolutely required for blood cell generation, each one controlling a precise step of specification from the mesoderm germ layer to fully functional blood progenitors 31432499
2019-03-09 10:44:00 ETS transcription factor Etv2, a critical factor for haematopoietic and vascular development, is also required for haematopoietic regeneration. Etv2, which is silent in homeostatic HSCs, was transiently activated in regenerating HSPCs and was required for the HSC expansion and regeneration following bone marrow transplantation or haematopoietic injury. 29697486

名称对应

Type IDs
Synonymous ER71, ETSRP71
Gene
UniProtKB-ID: ETV2_HUMAN, Q3KNT2_HUMAN, K7ERX2_HUMAN
UniprotKB: O00321, Q3KNT2, K7ERX2
UniParc: UPI0000185F5F, UPI0000202119, UPI000013C7F7, UPI00005C40CB
EMBL: AF000671, BC140746, BC107124, AC002115, AK097439
Ensembl: ENSG00000105672
KO: hsa:2116
Nucleutide sequences
EMBL-CDS: BAG53472.1, AAI40747.1, AAB57630.1, AAD00861.1, AAI07125.1
Ensembl_TRS: ENST00000403402, ENST00000379026, ENST00000402764, ENST00000379023, ENST00000479824
Protein sequencees
Ensembl_PRO: ENSP00000385369, ENSP00000368312, ENSP00000384524, ENSP00000368309, ENSP00000468453
RefSeq: XP_011524926.1, XP_016881961.1, NP_001291478.1, NP_055024.2, XP_005258709.1, NP_001287903.1
Others
UniRef100: UniRef100_O00321, UniRef100_Q3KNT2, UniRef100_K7ERX2
UniRef90: UniRef90_O00321, UniRef90_A0A2I3GPV8
UniRef50: UniRef50_A0A452S3Y9, UniRef50_O00321
UniGene: Hs.194061
CCDS: CCDS32995.2

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