| Type | Description |
|---|---|
| Definition | leucine zipper, putative tumor suppressor 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-28 11:17:00 | Lzts1 functions as a master modulator of cellular dynamics, contributing to increasing complexity of the cerebral architecture during evolution. | 31239441 |
| 2016-01-30 11:45:00 | The results of this study provide a novel Rap2-specific regulatory mechanism in synaptic maturation involving PSD-Zip70. | 26490870 |
| 2012-09-22 10:37:00 | Taken together, the spatial and temporal distribution of Lzts1 is consistent with a potential function(s) in cell cycle regulation, axon growth or guidance, and/or migration of neurons. | 22419569 |
| 2010-01-21 00:00:00 | Partial or complete loss of Lzts1 downregulates Cdc25C and inhibits Cdk1 activity during mitosis, leading to premature transition from metaphase to anaphase. | 17419986 |
| 2010-01-21 00:00:00 | Loss of one or both LZTS1 alleles hampers the normal defenses of urothelial cells against carcinogens, favoring bladder cancer development, which may make FEZ1 a target for gene therapy. | 18192690 |
| Type | IDs |
|---|---|
| Synonymous | F37, FEZ1, PSD-Zip70 |
| Gene |
UniProtKB-ID:
LZTS1_MOUSE
UniprotKB:
P60853
UniParc:
UPI00000241D8
EMBL:
AF288601,
BC139350,
BC139352
Ensembl:
ENSMUSG00000036306
KO:
mmu:211134
|
| Nucleutide sequences |
EMBL-CDS:
AAQ14349.1,
AAI39351.1,
AAI39353.1
Ensembl_TRS:
ENSMUST00000185176,
ENSMUST00000037049
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000039397,
ENSMUSP00000139117
RefSeq:
XP_006509671.1,
XP_030099245.1,
XP_030099244.1,
NP_001357900.1,
NP_955396.2
|
| Others |
UniRef100:
UniRef100_P60853
UniRef90:
UniRef90_P60853
UniRef50:
UniRef50_P60853
UniGene:
Mm.479807
CCDS:
CCDS22345.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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