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210529 Mettl14

210529

Mettl14

methyltransferase like 14

protein-coding

Mus musculus

基因描述

Type Description
Definition methyltransferase like 14

研究结论

Date Results Publications
2021-03-20 13:33:00 N(6)-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation. 33220174
2021-03-20 13:25:00 The N6-methyladenosine mRNA methylase METTL14 promotes renal ischemic reperfusion injury via suppressing YAP1. 31318098
2020-05-09 12:57:00 METTL14 deficiency in beta-cells increased cell death, altered cell differentiation, and decreased beta-cell mass and insulin secretion, leading to glucose intolerance. Mettl14 deletion is due to unique functions of m6A methylation in beta-cells mediated through other reader proteins or caused by secondary effects following chronically altered beta-cell functions. 31029827
2020-04-04 11:42:00 conditional inactivation of an essential N(6)-methyladenosine writer component, METTL14, results in decreased oligodendrocyte numbers and CNS hypomyelination, although oligodendrocyte precursor cell numbers are normal. 31901304
2019-12-07 10:38:00 These results suggest that acute METTL14 deficiency in beta-cells induces glucose intolerance by increasing the IRE1alpha/sXBP-1 pathway. 31369074

名称对应

Type IDs
Synonymous G430022H21Rik, mKIAA1627
Gene
UniProtKB-ID: MET14_MOUSE
UniprotKB: Q3UIK4
UniParc: UPI00001C2D8A, UPI000166301A
EMBL: AK146881, BC052204, AK129409
Ensembl: ENSMUSG00000028114
KO: mmu:210529
Nucleutide sequences
EMBL-CDS: AAH52204.1, BAC98219.1, BAE27502.1
Ensembl_TRS: ENSMUST00000029759
Protein sequencees
Ensembl_PRO: ENSMUSP00000029759
RefSeq: NP_964000.2
Others
UniRef100: UniRef100_Q3UIK4
UniRef90: UniRef90_Q9HCE5
UniRef50: UniRef50_Q9HCE5
UniGene: Mm.260039
CCDS: CCDS38622.1

全选

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