| Type | Description |
|---|---|
| Definition | synaptotagmin II |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 13:12:00 | These results suggest a physiological role for IPMK in regulating expression of Syt2. | 31221192 |
| 2018-02-03 10:51:00 | Authors propose that the strong reduction of Syt2 and SV2B are key factors of the functional synaptic alteration and that the physiological downregulation of Syt1 plays a determinant role in muscle vulnerability in SMA | 28173138 |
| 2017-12-16 12:11:00 | Deletion of Syt2 severely reduced and delayed disynaptic inhibition following parallel fiber stimulation and as release sensor at GABAergic basket cell-Purkinje cell synapses ensures fast and efficient feedforward inhibition in cerebellar microcircuit. | 28099850 |
| 2017-11-26 00:10:00 | aM inhibitors or the inhibition of the Ca(2+)-calmodulin-Munc13-1 signaling pathway only impaired the uptake of Syt2 while leaving membrane retrieval intact, indicating different recycling mechanisms for membranes and vesicle proteins. Our data identify a novel mechanism of stimulus- and Ca(2+)-dependent regulation of coordinated endocytosis of synaptic membranes and vesicle proteins. | 27154627 |
| 2017-08-05 12:41:00 | we identify Syt2 as a functionally important Ca(2+) sensor at fast-releasing inhibitory synapses, and show that Syt1 and Syt2 can redundantly control transmitter release at specific brain synapses | 28363983 |
| Type | IDs |
|---|---|
| Synonymous | IP4BP, R74640, mKIAA4194, sytII |
| Gene |
UniProtKB-ID:
SYT2_MOUSE,
A0A0R4J2C2_MOUSE
UniprotKB:
P46097,
A0A0R4J2C2
UniParc:
UPI00000228EC,
UPI00000295EB
EMBL:
D37793,
AC131591,
AK036357,
AC122771,
AF257303,
BC027019,
AF257304
Ensembl:
ENSMUSG00000026452
KO:
mmu:20980
|
| Nucleutide sequences |
EMBL-CDS:
BAC29397.1,
AAH27019.1,
BAA07041.1,
AAF68987.1,
AAF68988.1
Ensembl_TRS:
ENSMUST00000121990,
ENSMUST00000188842
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000112438,
ENSMUSP00000140081
RefSeq:
XP_006529387.1,
XP_006529385.1,
NP_001342655.1,
XP_036019046.1,
NP_033333.2
|
| Others |
UniRef100:
UniRef100_P46097,
UniRef100_A0A0R4J2C2
UniRef90:
UniRef90_P46097
UniRef50:
UniRef50_P21707
UniGene:
Mm.5102
CCDS:
CCDS15312.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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