| Type | Description |
|---|---|
| Definition | HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:13:00 | HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases. | 32366477 |
| 2019-01-05 10:53:00 | Authors show that the genetic ablation of hace1 in the YAC128 mouse model of HD accelerates motor deficits and exacerbates cognitive and psychiatric phenotypes in vivo. | 29121340 |
| 2017-09-30 13:39:00 | HACE1 controls TNF-elicited cell fate decisions and exerts tumor suppressor and anti-inflammatory activities via a TNFR1-RIP3 kinase-necroptosis pathway. | 27160902 |
| 2015-10-10 11:07:00 | Increased reactive oxygen species production due to Hace1 loss leads to glutamine addiction as a mechanism to cope with increased oxidative stress. | 25284589 |
| 2014-12-06 11:27:00 | Data indicate that HECT E3 ubiquitin ligase HACE1 deficiency accelerates pressure overload-induced heart failure. | 24614889 |
| Type | IDs |
|---|---|
| Synonymous | 1700042J16Rik, A730034A22Rik, BC025474 |
| Gene |
UniProtKB-ID:
HACE1_MOUSE
UniprotKB:
Q3U0D9
UniParc:
UPI0000F3BE32,
UPI0000F3BE31,
UPI00024B9D19,
UPI00001934E8
EMBL:
BC120697,
BC025227,
AC135669,
BC025474,
AC153847,
AK042879,
BC120695,
AK220383,
AK156958
Ensembl:
ENSMUSG00000038822
KO:
mmu:209462
|
| Nucleutide sequences |
EMBL-CDS:
AAH25474.1,
AAI20696.1,
AAI20698.1,
AAH25227.1,
BAE33915.1,
BAD90440.1,
BAC31390.1
Ensembl_TRS:
ENSMUST00000037044
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000039206
RefSeq:
XP_006512699.1,
XP_036011610.1,
XP_036011611.1,
XP_030100843.1,
XP_030100842.1,
XP_006512701.1,
NP_766061.2,
XP_017169354.1,
XP_006512698.1,
XP_006512697.1,
XP_006512700.1,
XP_036011612.1
|
| Others |
UniRef100:
UniRef100_Q3U0D9
UniRef90:
UniRef90_Q8IYU2
UniRef50:
UniRef50_Q8IYU2
UniGene:
Mm.458633
CCDS:
CCDS23829.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员