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209446 Tfe3

209446

Tfe3

transcription factor E3

protein-coding

Mus musculus

基因描述

Type Description
Definition transcription factor E3

研究结论

Date Results Publications
2020-09-19 16:22:00 Myeloid Folliculin balances mTOR activation to maintain innate immunity homeostasis. 30843872
2020-05-30 11:55:00 The Fnip1-deficient B cell progenitors exhibited increased nuclear localization of transcription factor binding to IgHM enhancer 3 (TFE3) in developing B cells, which correlated with an increased expression of TFE3-target genes, increased lysosome numbers and function, and increased autophagic flux. 31676673
2020-04-18 10:43:00 TFE3 Xp11.2 Translocation resulting in high TFE3 expression is associated with Renal Cell Carcinoma. 31043488
2020-03-28 12:14:00 lysosome activity, the Ragulator protein complex, and the tumor-suppressor protein Folliculin enable the Rag GTPases C and D to bind and seclude the bHLH transcription factor Tfe3 in the cytoplasm. 30595499
2020-01-04 10:32:00 Comparative analysis of the cistromes of TFEB/TFE3 and REV-ERBalpha showed an extensive overlap of their binding sites, particularly in genes involved in autophagy and metabolic functions. 31126958

名称对应

Type IDs
Synonymous F830016E06Rik, Tcfe3, Tfe-3, bHLHe33
Gene
UniProtKB-ID: TFE3_MOUSE, Q3U1L5_MOUSE, A2AEW0_MOUSE, Q8K420_MOUSE, A2AEW1_MOUSE
UniprotKB: Q64092, Q3U1L5, A2AEW0, Q8K420, A2AEW1
UniParc: UPI0000EADF5A, UPI00005ACBA5, UPI0000028AA6, UPI00001B9826, UPI00000EB26A, UPI00005ACF8C, UPI0000435B31, UPI00005ABF34
EMBL: AK089762, AK152221, AK139756, BC063047, AK155883, AF510653, AL671995, BC056358, AK144657, S76673
Ensembl: ENSMUSG00000000134
KO: mmu:209446
Nucleutide sequences
EMBL-CDS: AAH63047.1, AAB21130.1, AAH56358.1, BAC40955.1, BAE31048.1, BAE24128.1, BAE25994.1, BAE33481.1, AAM95608.1
Ensembl_TRS: ENSMUST00000101695, ENSMUST00000137467, ENSMUST00000115678, ENSMUST00000115679, ENSMUST00000115677, ENSMUST00000079542, ENSMUST00000077680
Protein sequencees
Ensembl_PRO: ENSMUSP00000099219, ENSMUSP00000134125, ENSMUSP00000111343, ENSMUSP00000111342, ENSMUSP00000111341, ENSMUSP00000078498, ENSMUSP00000076864
RefSeq: XP_036017793.1, NP_001258418.1, NP_766060.2, XP_017173943.1, NP_001258419.1, XP_036017791.1, NP_001258420.1, XP_036017792.1, XP_017173942.1, XP_006527641.1, NP_001098666.1, NP_001098667.1
Others
UniRef100: UniRef100_Q64092-3, UniRef100_A2AEW0, UniRef100_A2AEW1, UniRef100_Q64092
UniRef90: UniRef90_Q64092-3, UniRef90_Q64092
UniRef50: UniRef50_P19532
UniGene: Mm.249142
CCDS: CCDS72333.1, CCDS52985.1, CCDS72332.1, CCDS52984.1

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