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20937 Suv39h1

20937

Suv39h1

suppressor of variegation 3-9 1

protein-coding

Mus musculus

基因描述

Type Description
Definition suppressor of variegation 3-9 1

研究结论

Date Results Publications
2021-02-13 13:20:00 Extreme disruption of heterochromatin is required for accelerated hematopoietic aging. 32305044
2020-09-05 20:37:00 Interplay among H3K9-editing enzymes SUV39H1, JMJD2C and SRC-1 drives p66Shc transcription and vascular oxidative stress in obesity. 29077881
2020-05-23 10:48:00 Tumor-infiltrating cytotoxic T-Lymphocytes (CTLs) in the colon tumor microenvironment have high expression of the H3K9me3-specific histone methyltransferase (SUV39H1). SUV39H1 enzyme inhibitor F5446 inhibits H3K9me3, thereby upregulating the expression CTL effector genes and suppressing colon carcinoma growth in a CD8(+) CTL-dependent manner. 30610059
2019-11-16 13:57:00 Removal of the acetyl-group at K230 in Sirt1 due to the absence of Sirt7 leads to hyperactivation of Sirt1 and thereby to constantly increased activity of Suv39h1. 29963979
2019-10-05 11:52:00 CRL4-DCAF13-mediated SUV39H1 degradation is an essential step for progressive genome reprogramming during preimplantation embryonic development. 30111536

名称对应

Type IDs
Synonymous AI852103, AL022883, DXHXS7466e, H3-K9-HMTase 1, KMT1A, mIS6
Gene
UniProtKB-ID: SUV91_MOUSE, A2AC19_MOUSE
UniprotKB: O54864, A2AC19
UniParc: UPI000002B460, UPI00001F8006, UPI00000019CB, UPI00005ABF35
EMBL: AL663032, AF149203, BC023860, AF193861, AK139757, AF019969, AK169389, AF193862, AK088405
Ensembl: ENSMUSG00000039231
KO: mmu:20937
Nucleutide sequences
EMBL-CDS: AAB92225.1, BAE41136.1, AAF60970.1, BAC40334.1, BAE24129.1, AAH23860.1, AAF73151.1, AAF60969.1
Ensembl_TRS: ENSMUST00000115638, ENSMUST00000115636, ENSMUST00000115637
Protein sequencees
Ensembl_PRO: ENSMUSP00000111299, ENSMUSP00000111301, ENSMUSP00000111300
RefSeq: NP_001345166.1, XP_006527637.1, XP_030107150.1, NP_035644.1, NP_001277645.1, XP_011245754.1
Others
UniRef100: UniRef100_A2AC19, UniRef100_O54864
UniRef90: UniRef90_A2AC19, UniRef90_O54864
UniRef50: UniRef50_A0A2K5CGQ4, UniRef50_O54864
UniGene: Mm.9244, Mm.479743
CCDS: CCDS40846.1

全选

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