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20928 Abcc9

20928

Abcc9

ATP-binding cassette, sub-family C (CFTR/MRP), member 9

protein-coding

Mus musculus

基因描述

Type Description
Definition ATP-binding cassette, sub-family C (CFTR/MRP), member 9

研究结论

Date Results Publications
2020-11-21 13:13:00 Glibenclamide reverses cardiovascular abnormalities of Cantu syndrome driven by KATP channel overactivity. 31821173
2018-03-24 11:36:00 Cardiac SUR2A levels were significantly increased while Kir6.2 levels were not affected. Hypoxia did not induce phosphorylation of extracellular signal-regulated kinases (ERK1/2) or protein kinase B (Akt), but triggered phosphorylation of AMP activated protein kinase (AMPK). AICAR, an activator of AMPK, increased the level of SUR2A in H9c2 cells. We conclude that oxygen increases SUR2A level by activating AMPK. 28121062
2017-05-27 11:17:00 K(ATP) channels seem to play an essential role in murine myometrial motility via activation of SUR2B and Kir6.2 27086859
2015-10-03 10:04:00 Data show that PI3K/Akt signalling pathway and lactate dehydrogenase (LDH) play a crucial role in increase of cardiac ATP-binding cassette transporter sub-family C member 9 (SUR2A) induced by in vivo exposure to 18% oxygen. 25576887
2015-05-16 10:08:00 Sulfhydration of SUR2B subunit modifies tyrosine nitration of Kir6.1 subunit within the KATP channel complex. 25552582

名称对应

Type IDs
Synonymous AI414027, AI449286, SUR2A, SUR2B, Sur2
Gene
UniProtKB-ID: ABCC9_MOUSE, E9PUE8_MOUSE
UniprotKB: P70170, E9PUE8
UniParc: UPI000002A32C, UPI0000028EDE, UPI0000DDA848, UPI0000029E24
EMBL: U97066, D86038, AF003531, AC121611, D86037
Ensembl: ENSMUSG00000030249
KO: mmu:20928
Nucleutide sequences
EMBL-CDS: AAB58753.1, BAA12969.2, AAB58701.1, BAA12970.2
Ensembl_TRS: ENSMUST00000087527, ENSMUST00000100827, ENSMUST00000073173, ENSMUST00000205202, ENSMUST00000111771
Protein sequencees
Ensembl_PRO: ENSMUSP00000144779, ENSMUSP00000098390, ENSMUSP00000072914, ENSMUSP00000084805, ENSMUSP00000107401
RefSeq: NP_066378.1, NP_066379.2, NP_001297072.1, XP_006507015.1, XP_006507013.1, NP_035641.1, XP_036021897.1, NP_001038185.1, XP_006507014.1, XP_006507012.1, XP_036021895.1, XP_036021896.1
Others
UniRef100: UniRef100_P70170, UniRef100_E9PUE8
UniRef90: UniRef90_P70170
UniRef50: UniRef50_Q63563
UniGene: Mm.35670, Mm.395475
CCDS: CCDS39696.1, CCDS39697.1, CCDS39699.1

全选

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