| Type | Description |
|---|---|
| Definition | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:59:00 | Activation of A signaling mitigates congenital hyperinsulinism associated hypoglycemia in the Sur1-/- mouse model. | 32735622 |
| 2018-07-07 12:00:00 | The findings of this study demonstrated a novel molecular mechanism involving the SUR1-TRPM4-AQP4 complex to account for bulk water influx during astrocyte swelling | 28906027 |
| 2017-08-05 10:43:00 | Despite its importance in central nervous system (CNS) injuries, sulfonylurea receptor 1 (SUR1) upregulation appears to play no part in rodent anterior ischemic optic neuropathy (rAION) injury. | 27560494 |
| 2016-02-20 10:28:00 | study provides evidence for a role of Abcc8(ATP-binding cassette sub-family C) in early-phase glucose-mediated insulin secretion and validates this gene as a contributor to beta-cell dysfunction in type 2 diabetes | 26493453 |
| 2013-12-28 11:49:00 | We conclude that the gradual development of glucose intolerance in patients with the SUR1-E1506K mutation might, as in the mouse model, result from impaired insulin secretion due a failure of insulin content to increase with age. | 23903354 |
| Type | IDs |
|---|---|
| Synonymous | D930031B21Rik, SUR1, Sur |
| Gene |
UniProtKB-ID:
B2RUS7_MOUSE
UniprotKB:
B2RUS7
UniParc:
UPI00004F8E1D
EMBL:
BC141411,
AC120135,
AC115036
Ensembl:
ENSMUSG00000040136
|
| Nucleutide sequences |
EMBL-CDS:
AAI41412.1
Ensembl_TRS:
ENSMUST00000033123
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000033123
RefSeq:
NP_035640.2,
XP_036008753.1,
NP_001344467.1,
XP_030098176.1,
XP_006540812.1
|
| Others |
UniRef100:
UniRef100_B2RUS7
UniRef90:
UniRef90_B2RUS7
UniRef50:
UniRef50_Q09428
UniGene:
Mm.259076
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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