| Type | Description |
|---|---|
| Definition | suppressor of Ty 6 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:07:00 | Iws1 and Spt6 Regulate Trimethylation of Histone H3 on Lysine 36 through Akt Signaling and are Essential for Mouse Embryonic Genome Activation. | 30846735 |
| 2019-04-06 10:21:00 | SPT6 facilitates IFN-induced transcription, highlighting its critical role in gene activation. | 29683485 |
| 2019-02-16 10:12:00 | Iws1 is expressed in all adult organs and it is an essential gene for mouse embryonic development. | 30208029 |
| 2017-10-28 11:29:00 | Biochemical as well as functional experiments revealed that Spt6 could compete for binding of the PRC2 methyltransferase Ezh2 to Suz12 and reduce PRC2 chromatin engagement. | 29033324 |
| 2013-06-22 12:10:00 | These data indicate that, through cooperation with PolII and KDM6A, Spt6 orchestrates removal of H3K27me3, thus controlling developmental gene expression and cell differentiation. | 23503590 |
| Type | IDs |
|---|---|
| Synonymous | 5131400N11Rik, AI132449, SPT6, Supt6h, mKIAA0162 |
| Gene |
UniProtKB-ID:
SPT6H_MOUSE,
Q3UWU8_MOUSE,
Q3TY72_MOUSE
UniprotKB:
Q62383,
Q3UWU8,
Q3TY72
UniParc:
UPI0000020C05,
UPI00005ABC4A,
UPI00005AD23D
EMBL:
BC072657,
U40375,
AL591070,
AK136094,
AK158846,
AK046156,
AK129069
Ensembl:
ENSMUSG00000002052
KO:
mmu:20926
|
| Nucleutide sequences |
EMBL-CDS:
BAC32616.1,
BAC97879.1,
AAH72657.1,
AAB18950.1,
BAE22816.1,
BAE34691.1
Ensembl_TRS:
ENSMUST00000002121
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000002121
RefSeq:
XP_006532806.1,
NP_033323.2
|
| Others |
UniRef100:
UniRef100_Q62383
UniRef90:
UniRef90_Q7KZ85
UniRef50:
UniRef50_Q7KZ85
UniGene:
Mm.20755
CCDS:
CCDS25095.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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