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20911 Stxbp2

20911

Stxbp2

syntaxin binding protein 2

protein-coding

Mus musculus

基因描述

Type Description
Definition syntaxin binding protein 2

研究结论

Date Results Publications
2019-10-19 10:03:00 results indicate that Munc18-2, but not Munc18-1 or Munc18-3, is essential for regulated exocytosis in platelets and platelet participation in thrombosis and hemostasis. 30696774
2019-05-04 10:19:00 Loss of Munc18-2/Stxbp2 recapitulated the pathologic features observed in patients with MUNC18-2 deficiency. 30364784
2019-01-26 12:13:00 observed an almost complete absence of exocytosis in Munc18-2-deficient MCs but intact exocytosis in MCs lacking Munc18-1 or Munc18-3 29599294
2018-10-06 10:24:00 SNARE zippering requires activation by SNARE-like peptides in Sec1/Munc18 proteins 30127032
2012-11-17 11:11:00 Munc18b as an essential gene that is a limiting component of the exocytic machinery of epithelial cells and mast cell. 22694344

名称对应

Type IDs
Synonymous C79054, Munc-18-2, Munc-18b, Munc18b, Sxtbp2, Sxtp2, Unc18-2, Unc18b, muSec1
Gene
UniProtKB-ID: STXB2_MOUSE, Q548T0_MOUSE
UniprotKB: Q64324, Q548T0
UniParc: UPI0000000822
EMBL: D42068, AF263346, AF263345, BC008102, U19520, AK088364, AK133419
Ensembl: ENSMUSG00000004626
KO: mmu:20911
Nucleutide sequences
EMBL-CDS: AAH08102.1, BAA07666.1, AAA69912.1, AAF71615.1, AAF71616.1, BAE21647.1, BAC40304.1
Ensembl_TRS: ENSMUST00000160708
Protein sequencees
Ensembl_PRO: ENSMUSP00000125405
RefSeq: XP_030099231.1, XP_017168121.1, XP_030099234.1, NP_001344097.1, NP_035633.1, XP_030099233.1, XP_030099236.1, XP_006508806.3, XP_011240348.1, XP_030099235.1, XP_006508809.1
Others
UniRef100: UniRef100_Q64324
UniRef90: UniRef90_Q15833
UniRef50: UniRef50_Q15833
UniGene: Mm.7247
CCDS: CCDS22067.1

全选

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