| Type | Description |
|---|---|
| Definition | syntaxin binding protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:38:00 | Stxbp1/Munc18-1 haploinsufficiency impairs inhibition and mediates key neurological features of STXBP1 encephalopathy. | 32073399 |
| 2021-04-13 10:15:00 | Munc13 activates the Munc18-1/syntaxin-1 complex and enables Munc18-1 to prime SNARE assembly. | 32643828 |
| 2021-01-09 13:26:00 | Essential Role of Syntaxin-Binding Protein-1 in the Regulation of Glucagon-Like Peptide-1 Secretion. | 32141504 |
| 2020-11-21 13:32:00 | A Munc18-1 mutant mimicking phosphorylation by Down Syndrome-related kinase Dyrk1a supports normal synaptic transmission and promotes recovery after intense activity. | 32081899 |
| 2020-07-25 11:13:00 | The results demonstrate that MUNC18-1 regulates the F-actin network independently of syntaxin1 targeting via hydrophobicity in beta-sheet 10. The abnormally dense F-actin network in Munc18-1-deficient cells is not a rate-limiting barrier in secretory vesicle docking or fusion. | 31719162 |
| Type | IDs |
|---|---|
| Synonymous | AI317162, AI326233, MMS10-G, Ms10g, Munc-18a, Munc18-1, N-sec1, Rb-sec1, Sxtbp1, Unc18-1, Unc18h, nsec1 |
| Gene |
UniProtKB-ID:
STXB1_MOUSE
UniprotKB:
O08599
UniParc:
UPI0000006C0B,
UPI0000000ED9
EMBL:
AL845471,
AB012697,
AF326545,
AF326563,
D45903,
BC031728
Ensembl:
ENSMUSG00000026797
KO:
mmu:20910
|
| Nucleutide sequences |
EMBL-CDS:
BAA19479.1,
AAL37409.1,
AAH31728.1,
AAL37391.1,
CAM20727.1,
CAM20726.1,
CAM20728.1,
BAA32486.1
Ensembl_TRS:
ENSMUST00000050000,
ENSMUST00000077458
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000089051,
ENSMUSP00000052440
RefSeq:
NP_033321.2,
NP_001107041.1
|
| Others |
UniRef100:
UniRef100_P61764
UniRef90:
UniRef90_P61764
UniRef50:
UniRef50_P61764
UniGene:
Mm.278865
CCDS:
CCDS50572.1,
CCDS15933.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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