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2091 FBL

2091

FBL

fibrillarin

protein-coding

Homo sapiens

基因描述

Type Description
Definition fibrillarin

研究结论

Date Results Publications
2021-02-27 13:49:00 Fibrillarin Ribonuclease Activity is Dependent on the GAR Domain and Modulated by Phospholipids. 32384686
2020-03-07 12:43:00 This is the first report on the clinical aspect of ribosome biogenesis in pediatric BCP-ALL [B-cell precursor acute lymphoblastic leukemia ], and it shows that overexpression of CMYC and C/D box nucleoproteins FBL and NOP56 is an antecedent event in patients who subsequently relapse. 32011831
2019-12-07 10:31:00 SIRT7-dependent deacetylation impacts nucleolar activity by an FBL-driven circuitry that mediates cell-cycle-dependent fluctuation of ribosomal DNA transcription. 30540930
2018-12-29 12:32:00 Fibrillarin acts as a central node in a regulatory network engaged in imparting immunity against bacterial pathogens. 30190478
2017-01-14 11:43:00 Nucleolar Methyltransferase Fibrillarin: Evolution of Structure and Functions. 27682166

名称对应

Type IDs
Synonymous FIB, FLRN, Nop1, RNU3IP1
Gene
UniProtKB-ID: FBRL_HUMAN
UniprotKB: P22087
UniParc: UPI000012A578
EMBL: BT020144, BT006830, BC019260, AC005393, M59849, X56597, CR457069, AC006950, CH471126, AB451384
Ensembl: ENSG00000105202, ENSG00000280548
KO: hsa:2091
Nucleutide sequences
EMBL-CDS: AAD15623.1, AAC28913.1, AAH19260.1, AAV38946.1, BAG70198.1, CAA39935.1, EAW56925.1, AAA52453.1, CAG33350.1, AAP35476.1
Ensembl_TRS: ENST00000625241, ENST00000221801
Protein sequencees
Ensembl_PRO: ENSP00000221801, ENSP00000487390
RefSeq: NP_001427.2, XP_011524925.1, XP_005258708.1
Others
UniRef100: UniRef100_P22087
UniRef90: UniRef90_P22087
UniRef50: UniRef50_P22087
UniGene: Hs.299002
CCDS: CCDS12545.1

全选

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研究热度

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