| Type | Description |
|---|---|
| Definition | tensin 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-10 13:00:00 | Tensin2 is important for podocyte-glomerular basement membrane interaction and integrity of the glomerular filtration barrier. | 32390516 |
| 2017-06-24 10:28:00 | deficiency causes alteration of actin remodeling and morphological changes in podocytes and subsequent proteinuria | 27246398 |
| 2014-07-26 10:02:00 | Data suggest that Tenc1 (tensin2) contributes to the maintenance of glomerular basement membrane (GBM) structures and that the genetic background influences the severity of nephrotic syndrome. | 23988887 |
| 2013-06-15 12:07:00 | DISC1-Tensin2 colocalisation was most clearly observed in the Purkinje cells of the mouse cerebellum. | 23233134 |
| 2013-06-15 11:33:00 | C1-Ten is a novel protein tyrosine phosphatase (PTPase) of IRS-1 that acts as a mediator to reduce IRS-1 under a catabolic condition, resulting in muscle atrophy. C1-Ten preferentially dephosphorylated Y612 of IRS-1, which accelerated IRS-1 degradation. | 23401856 |
| Type | IDs |
|---|---|
| Synonymous | C1-ten, Tenc1, nep, nph |
| Gene |
UniProtKB-ID:
TNS2_MOUSE
UniprotKB:
Q8CGB6
UniParc:
UPI00000E8EE8,
UPI0000473F70,
UPI000153BFD0,
UPI0000354DA4
EMBL:
AK147789,
AK158009,
BC042190,
BC025818,
AF424789
Ensembl:
ENSMUSG00000037003
KO:
mmu:209039
|
| Nucleutide sequences |
EMBL-CDS:
BAE34316.1,
BAE28139.1,
AAH25818.1,
AAN32753.1,
AAH42190.1
Ensembl_TRS:
ENSMUST00000169627,
ENSMUST00000228958,
ENSMUST00000046144
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000129146,
ENSMUSP00000041087,
ENSMUSP00000155830
RefSeq:
XP_030104299.1,
NP_001342565.1,
XP_006520757.1,
XP_006520754.1,
NP_705761.2,
XP_006520755.1,
XP_006520756.1
|
| Others |
UniRef100:
UniRef100_Q8CGB6
UniRef90:
UniRef90_Q8CGB6
UniRef50:
UniRef50_Q63HR2
UniGene:
Mm.29389
CCDS:
CCDS37224.1,
CCDS88852.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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