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208936 Adamts18

208936

Adamts18

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18

protein-coding

Mus musculus

基因描述

Type Description
Definition a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18

研究结论

Date Results Publications
2020-09-05 13:53:00 Genetic manipulation of ureteric bud tip progenitors in the mammalian kidney through an Adamts18 enhancer driven tet-on inducible system. 31734175
2020-07-18 11:39:00 Adamts18 links luminal hormone receptor signaling to basement membrane remodeling and stem cell activation. 32218432
2018-03-17 12:10:00 The underlying molecular mechanisms could be attributed in part to the abnormal vascular remodeling, including deficiency of carotid body (glomus) and aberrant carotid basal lamina. These results indicate a novel function of ADAMTS18 in vascular remodeling and associated thrombus formation. 29421655
2017-09-23 11:37:00 Adamts18 deficiency enhances tumorigenesis and intestinal inflammation through elevated Wnt/beta-catenin and p38MAPK/ERK1/2 signaling and promotes colon cancer in a mouse model. 28145888
2012-05-12 11:11:00 these data demonstrate a thrombin cleavage site and confirm a short form of ADAMTS-18 presents in vivo. 22386991

名称对应

Type IDs
Synonymous 9630038L21, ADAMTS21, E130314N14Rik
Gene
UniProtKB-ID: ATS18_MOUSE
UniprotKB: Q4VC17
UniParc: UPI0000D62F88
EMBL: BC094674, AK035797, AC108856, AC125463
Ensembl: ENSMUSG00000053399
KO: mmu:208936
Nucleutide sequences
EMBL-CDS: BAC29190.1, AAH94674.1
Ensembl_TRS: ENSMUST00000093113
Protein sequencees
Ensembl_PRO: ENSMUSP00000090801
RefSeq: XP_006530858.1, XP_006530864.1, XP_030099230.1, XP_017168118.1, XP_030099229.1, XP_017168120.1, XP_006530860.1, XP_006530863.1, NP_766054.2
Others
UniRef100: UniRef100_Q4VC17
UniRef90: UniRef90_Q4VC17
UniRef50: UniRef50_Q4VC17
UniGene: Mm.167471
CCDS: CCDS40485.1

全选

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