| Type | Description |
|---|---|
| Definition | aurora kinase A |
| Date | Results | Publications |
|---|---|---|
| 2020-04-25 12:26:00 | EGFR-Aurka Signaling Rescues Polarity and Regeneration Defects in Dystrophin-Deficient Muscle Stem Cells by Increasing Asymmetric Divisions | 30713094 |
| 2019-10-26 11:37:00 | in the absence of AURKC, AURKA localizes to chromosomes in a CPC-dependent manner. These data suggest that AURKC prevents AURKA from localizing to chromosomes by competing for CPC binding. This competition is important for adequate spindle length to support meiosis I. There is also a unique requirement for AURKB to negatively regulate AURKC to prevent aneuploidy. | 30415701 |
| 2018-12-01 10:07:00 | AURKA is expressed in several cell types in the testis. Spermatogonia and spermatocytes express AURKA as expected based on the known role of this kinase in cell division. Surprisingly, we also found AURKA localized to spermatids and the flagellum of spermatozoa. | 29842884 |
| 2018-08-25 10:48:00 | ex vivo cells derived from teratomas exhibited high self-renewal capacity that was linked to Aurora-A kinase activity and gave rise to lung metastasis when injected into the tail vein of immunocompromised mice. | 29393405 |
| 2017-11-25 15:47:00 | Aurora A and Plk4 are rate-limiting factors contributing to microtubule growth as the acentriolar oocyte resumes meiosis. | 28972102 |
| Type | IDs |
|---|---|
| Synonymous | AIRK1, ARK-1, AU019385, AW539821, Ark1, Aurora-A, Ayk1, IAK, IAK1, Stk6 |
| Gene |
UniProtKB-ID:
AURKA_MOUSE,
Q3TEY6_MOUSE
UniprotKB:
P97477,
Q3TEY6
UniParc:
UPI0000022C02,
UPI000002B44F
EMBL:
AK169363,
BC014711,
AK145968,
AK085861,
AF007817,
U80932,
BC005425,
U69106
Ensembl:
ENSMUSG00000027496
KO:
mmu:20878
|
| Nucleutide sequences |
EMBL-CDS:
BAC39557.1,
AAH14711.1,
AAH05425.1,
AAC12682.1,
AAB63205.1,
AAB62982.1,
BAE41112.1,
BAE26793.1
Ensembl_TRS:
ENSMUST00000109140,
ENSMUST00000109139,
ENSMUST00000028997
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000104767,
ENSMUSP00000104768,
ENSMUSP00000028997
RefSeq:
NP_001278114.1,
NP_035627.1,
XP_006499138.1
|
| Others |
UniRef100:
UniRef100_P97477
UniRef90:
UniRef90_P97477
UniRef50:
UniRef50_O14965
UniGene:
Mm.249363
CCDS:
CCDS17129.1,
CCDS71204.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员