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20877 Aurkb

20877

Aurkb

aurora kinase B

protein-coding

Mus musculus

基因描述

Type Description
Definition aurora kinase B

研究结论

Date Results Publications
2020-10-24 14:06:00 Salivary glands require Aurora Kinase B for regeneration after transient innate immune-mediated injury. 31383943
2019-10-26 11:37:00 in the absence of AURKC, AURKA localizes to chromosomes in a CPC-dependent manner. These data suggest that AURKC prevents AURKA from localizing to chromosomes by competing for CPC binding. This competition is important for adequate spindle length to support meiosis I. There is also a unique requirement for AURKB to negatively regulate AURKC to prevent aneuploidy. 30415701
2019-10-26 10:12:00 Aurora B causes mitotic arrest and participates in spindle assembly checkpoint via Mad2 and H3S10P, which is required for self-correction of aneuploidies 31264311
2018-08-25 12:15:00 The results propose a model in which Aurora B-mediated H2AX-phosphorylated serine 121 probably provide a platform for Aurora B autoactivation circuitry at centromeres and thus play a pivotal role in proper chromosome segregation. 27389782
2018-07-07 12:25:00 Data show that phosphorylated Ku70 S155 interacts with the Aurora B kinase and leads to inhibition of its activity. 27849008

名称对应

Type IDs
Synonymous AIM-1, AIRK2, AL022959, Aik2, Aim1, Ark2, AurB, IPL1, STK-1, Stk12, Stk5
Gene
UniProtKB-ID: AURKB_MOUSE
UniprotKB: O70126
UniParc: UPI0000021A68
EMBL: U69107, AK132006, BC003261, AK075951, AL645902, CH466601, D21099
Ensembl: ENSMUSG00000020897
KO: mmu:20877
Nucleutide sequences
EMBL-CDS: AAC12683.1, EDL10472.1, BAE20935.1, BAA04658.1, AAH03261.1, BAC36078.1
Ensembl_TRS: ENSMUST00000021277, ENSMUST00000108666
Protein sequencees
Ensembl_PRO: ENSMUSP00000021277, ENSMUSP00000104306
RefSeq: NP_035626.1, XP_006532788.1
Others
UniRef100: UniRef100_O70126
UniRef90: UniRef90_O70126
UniRef50: UniRef50_O70126
UniGene: Mm.3488
CCDS: CCDS24877.1

全选

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