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20874 Slk

20874

Slk

STE20-like kinase

protein-coding

Mus musculus

基因描述

Type Description
Definition STE20-like kinase

研究结论

Date Results Publications
2020-11-28 13:13:00 Loss of the Ste20-like kinase induces a basal/stem-like phenotype in HER2-positive breast cancers. 32393835
2020-10-10 12:59:00 Genetic ablation of SLK exacerbates glomerular injury in adriamycin nephrosis in mice. 32308020
2019-07-20 11:39:00 Podocyte-specific deletion of SLK leads to albuminuria, loss of podocytes, and morphological evidence of podocyte injury. Thus, SLK is essential to the maintenance of podocyte integrity. 29187370
2018-03-31 12:06:00 Loss of SLK impairs myofiber stability and function. 28153048
2018-01-13 12:02:00 kinases, including Slk, Lok and Mst1, are inhibited by BI-D1870 but to a much lesser extent by BIX 02565 and that phosphorylation of some of their substrates is blocked by BI-D1870 in living cells. 27919044

名称对应

Type IDs
Synonymous 9A2, AV021402, AW411554, Etk4, SMAK, Stk2, mKIAA0204, mSLK
Gene
UniProtKB-ID: SLK_MOUSE, A2RRK3_MOUSE
UniprotKB: O54988, A2RRK3
UniParc: UPI0000028CB7, UPI0000D60E0D
EMBL: AK029491, AF112855, AK037798, BC131674, AF039574, AK122218, BC131675
Ensembl: ENSMUSG00000025060
KO: mmu:20874
Nucleutide sequences
EMBL-CDS: AAB96682.1, BAC65500.1, BAC26474.1, BAC29874.1, AAD28717.1, AAI31676.1, AAI31675.1
Ensembl_TRS: ENSMUST00000051691, ENSMUST00000026043
Protein sequencees
Ensembl_PRO: ENSMUSP00000049977, ENSMUSP00000026043
RefSeq: XP_006526890.1, NP_033315.2, NP_001158111.1
Others
UniRef100: UniRef100_O54988, UniRef100_A2RRK3
UniRef90: UniRef90_O54988
UniRef50: UniRef50_Q9H2G2
UniGene: Mm.281011
CCDS: CCDS50465.1, CCDS38017.1

全选

研究热度
发表文献
研究结论
热点单位
排名 科研单位 文献
1

University of Ottawa

8
2

National Cancer Institute

3
3

Ottawa Hospital Research Institute

3
4

Zilkha Neurogenetic Institute

2
5

McGill University Health Centre Research Institute

2
热点人员
排名 研究人员 文献
1

Luc A Sabourin

10
2

P Carninci

7
3

Y Hayashizaki

6
4

H Konno

5
5

K Shibata

5
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