BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.

Cell Syst     Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

Nat Genet     David K Breslow , Sascha Hoogendoorn , Adam R Kopp , David W Morgens , Brandon K Vu , Margaret C Kennedy , Kyuho Han , Amy Li , Gaelen T Hess , Michael C Bassik , James K Chen , Maxence V Nachury

Maternal DNA Methylation Regulates Early Trophoblast Development.

Dev. Cell     Miguel R Branco , Michelle King , Vicente Perez-Garcia , Aaron B Bogutz , Matthew Caley , Elena Fineberg , Louis Lefebvre , Simon J Cook , Wendy Dean , Myriam Hemberger , Wolf Reik

A combination of SILAC and nucleotide acyl phosphate labelling reveals unexpected targets of the Rsk inhibitor BI-D1870.

Biosci Rep     Alexander J Edgar , Matthias Trost , Colin Watts , Rossana Zaru

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.

Brief. Bioinformatics     Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas

A conditional knockout resource for the genome-wide study of mouse gene function.

Nature     William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley

A high-resolution anatomical atlas of the transcriptome in the mouse embryo.

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LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation.

Proc. Natl. Acad. Sci. U.S.A.     Natalya V Belkina , Yin Liu , Jian-Jiang Hao , Hajime Karasuyama , Stephen Shaw

Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites.

EMBO J     Ashley C W Pike , Peter Rellos , Frank H Niesen , Andrew Turnbull , Antony W Oliver , Sirlester A Parker , Benjamin E Turk , Laurence H Pearl , Stefan Knapp

The transcriptional landscape of the mammalian genome.

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