| Type | Description |
|---|---|
| Definition | sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 |
| Date | Results | Publications |
|---|---|---|
| 2013-11-16 12:00:00 | hyposulfatemia leads to hepatic phosphoadenosine-5'-phosphosulfate depletion, which causes loss of SULT2A1 activity and results in accumulation of nonsulfated bile acids and activated farnesoid X receptor activation. | 23674610 |
| 2010-01-21 00:00:00 | Increased Sult2A1 expression appears to be an adaptive response to ensure optimal metabolism of Sult2A1 substrates at old age. | 15541768 |
| 2010-01-21 00:00:00 | hydroxysteroid sulfotransferase has a protective role in lithocholic acid-induced liver toxicity | 12637555 |
| 2010-01-21 00:00:00 | and Sult2a1 participate in an integrated pathway mediating elimination of sulfated steroid and bile acid metabolites from the liver | 15004017 |
| 2010-01-21 00:00:00 | decreased levels or activities of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor during the acute-phase response could contribute to decreases in Sult2A1, resulting in decreased sulfation of DHEA | 15198932 |
| Type | IDs |
|---|---|
| Synonymous | ST2A1, Std, Sth1, mSTa1 |
| Gene |
UniProtKB-ID:
ST2A1_MOUSE
UniprotKB:
P52843
UniParc:
UPI00000298AF
EMBL:
L02335
Ensembl:
ENSMUSG00000078798
KO:
mmu:20859
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000108522
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000104162
RefSeq:
NP_001104766.1
|
| Others |
UniRef100:
UniRef100_P52843
UniRef90:
UniRef90_P52843
UniRef50:
UniRef50_P52843
UniGene:
Mm.260026
CCDS:
CCDS52031.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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