| Type | Description |
|---|---|
| Definition | stanniocalcin 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-12 14:40:00 | STC-1 is a downstream effector molecule in latanoprost signaling that is independent of the F2a receptor, equivalent and non-additive in the early intraocular pressure response in wild-type mice | 32365129 |
| 2019-08-31 11:07:00 | The results suggest that Stc1 may be a downstream candidate of Gpnmb, and that both genes interact with other genes in a network to develop glaucoma through mechanisms such as apoptosis and oxidative stress. | 31057322 |
| 2017-07-22 11:48:00 | Latanoprost-induced reduction of intraocular pressure is mediated through the downstream signaling molecule STC-1. When used by itself, STC-1 exhibits ocular hypotensive properties. | 28538979 |
| 2017-04-01 12:41:00 | STC-1 maybe improve anti-inflammation, anti-oxidant and anti-apoptosis activities by affecting reactive oxygen species -mediated pathways, especially the phospho-modifications of the respective proteins, resulting in the increase of Superoxide dismutase and reduce of capase-3, p53, IL-6 and IFN-gamma. | 27420048 |
| 2016-10-22 11:28:00 | STC1 blunts bleomycin-induced rise in thrombin protein and activity, diminishes thrombin-induced signaling through PAR1 to ERK, and inhibits bleomycin-induced pneumonitis. | 26640170 |
| Type | IDs |
|---|---|
| Synonymous | Stc |
| Gene |
UniProtKB-ID:
STC1_MOUSE,
Q3UEW5_MOUSE,
Q3UYZ1_MOUSE
UniprotKB:
O55183,
Q3UEW5,
Q3UYZ1
UniParc:
UPI000002136B,
UPI00005AC872
EMBL:
AK149293,
U47815,
BC021425,
AK134260
Ensembl:
ENSMUSG00000014813
KO:
mmu:20855
|
| Nucleutide sequences |
EMBL-CDS:
AAC00050.1,
AAH21425.1,
BAE28796.1,
BAE22070.1
Ensembl_TRS:
ENSMUST00000014957
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000014957
RefSeq:
NP_033311.3
|
| Others |
UniRef100:
UniRef100_O55183,
UniRef100_Q3UEW5
UniRef90:
UniRef90_P97574
UniRef50:
UniRef50_P97574
UniGene:
Mm.20911
CCDS:
CCDS27236.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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