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208449 Sgms1

208449

Sgms1

sphingomyelin synthase 1

protein-coding

Mus musculus

基因描述

Type Description
Definition sphingomyelin synthase 1

研究结论

Date Results Publications
2020-07-11 12:17:00 Investigated role of sphingomyelin synthase 1 (SMS1) and sphingomyelin synthase 2 (SMS2) in osteoblast differentiation in order to better understand the role SMS1 and SMS2 play in skeletal development. 31847800
2019-12-21 12:39:00 optively transferred wide-type B cells partially recovered B-cell activation and autoantibody production in SMS1 deficient bm12-induced lupus mice. Moreover, the SMS1 mRNA level in B cells of SLE patients was increased and positively correlated with the serum anti-dsDNA level, IgG and globulin titers. 31262710
2019-06-29 11:28:00 2-Hydroxy-oleic acid inhibited rather than activated recombinant SMS1 (rSMS1) and rSMS2 in a dose-dependent fashion. 30305392
2019-04-13 10:57:00 Knockdown of SMS1 promotes lysosomal degradation of BACE1 and attenuates Alzheimer's disease-like pathology in transgenic mice. 30243987
2018-05-26 10:46:00 SMS1 contributed to sphingomyelin generation inducing Japanese encephalitis virus attachment and infection. 27892528

名称对应

Type IDs
Synonymous 9530058O11Rik, AI841905, C80702, Mob, Sms1, Sor1, Tmem23
Gene
UniProtKB-ID: SMS1_MOUSE
UniprotKB: Q8VCQ6
UniParc: UPI00000E9E35, UPI000023B840, UPI00000E9BAB
EMBL: AK146782, AK079254, AK160539, AK150272, AK133967, BC085298, BC019443, AK151170, AK152312, AK082974, AK076554, AK153406, AY509044
Ensembl: ENSMUSG00000040451
KO: mmu:208449
Nucleutide sequences
EMBL-CDS: BAC37590.1, BAE21960.1, BAE29428.1, BAE31117.1, AAH19443.2, AAH85298.1, BAE31966.1, BAC38717.1, BAE35856.1, BAE30173.1, BAC36390.1, AAS90514.1, BAE27428.1
Ensembl_TRS: ENSMUST00000151289, ENSMUST00000099514, ENSMUST00000142618, ENSMUST00000152340
Protein sequencees
Ensembl_PRO: ENSMUSP00000117336, ENSMUSP00000123395, ENSMUSP00000097114, ENSMUSP00000119869
RefSeq: XP_030106691.1, XP_030106697.1, XP_011245507.1, XP_006526883.1, NP_659041.3, NP_001161998.1, XP_011245505.1, XP_006526881.1, NP_001349352.1, XP_030106695.1, XP_017173594.1, XP_030106696.1, XP_011245504.1, XP_006526882.1, XP_030106693.1, NP_001161997.1, XP_030106692.1
Others
UniRef100: UniRef100_Q8VCQ6
UniRef90: UniRef90_Q86VZ5
UniRef50: UniRef50_Q86VZ5
UniGene: Mm.329810
CCDS: CCDS29750.1

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