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20844 Stam

20844

Stam

signal transducing adaptor molecule (SH3 domain and ITAM motif) 1

protein-coding

Mus musculus

基因描述

Type Description
Definition signal transducing adaptor molecule (SH3 domain and ITAM motif) 1

研究结论

Date Results Publications
2017-09-09 13:06:00 the motor neuron-specific ISL1-LHX3 complex directly transactivates the Stam1 gene. 27161150
2015-02-14 12:59:00 ESCRT-0 protein hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is targeted to endosomes independently of signal-transducing adaptor molecule (STAM) and the complex formation with STAM promotes its endosomal dissociation. 25296754
2010-01-21 00:00:00 Hrs is a master molecule that controls in part the degradation of STAM1 and the accumulation of ubiquitinated proteins 15640163
2010-01-21 00:00:00 These results demonstrate that the STAMs are indispensably involved in T-cell development and survival in the thymus through the prevention of apoptosis but are dispensable for the proximal signaling of TCR and cytokine receptors. 12446783
2010-01-21 00:00:00 plays important role in the mammalian endosomal/vacuolar protein sorting pathway 13679051

名称对应

Type IDs
Synonymous STAM1
Gene
UniProtKB-ID: STAM1_MOUSE, Q3TQ49_MOUSE
UniprotKB: P70297, Q3TQ49
UniParc: UPI000000B639
EMBL: BC055326, U43900, AK163922, BC044666, AK157767, AK169170
Ensembl: ENSMUSG00000026718
KO: mmu:20844
Nucleutide sequences
EMBL-CDS: AAH44666.1, AAH55326.1, AAC52840.1, BAE40949.1, BAE37536.1, BAE34187.1
Ensembl_TRS: ENSMUST00000102960
Protein sequencees
Ensembl_PRO: ENSMUSP00000100025
RefSeq: NP_001343266.1, NP_035614.1
Others
UniRef100: UniRef100_P70297
UniRef90: UniRef90_P70297
UniRef50: UniRef50_O75886
UniGene: Mm.273174
CCDS: CCDS15698.1

全选

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研究热度

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